515162-20-6Relevant articles and documents
Cyano-pyrrolo-heteroaryl derivative, preparation method thereof and application of derivative to medicine
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Paragraph 0254; 0255; 0256; 0257; 0262-0265, (2019/10/23)
The invention relates to a cyano-pyrrolo-heteroaryl derivative, a preparation method thereof and an application of the derivative to medicine, and particularly relates to a novel cyano-pyrrolo-heteroaryl derivative as shown in a general formula (I), a pre
Structural-based design, synthesis, and antitumor activity of novel alloxazine analogues with potential selective kinase inhibition
Malki, Waleed H.,Gouda, Ahmed M.,Ali, Hamdy E.A.,Al-Rousan, Rabaa,Samaha, Doaa,Abdalla, Ashraf N.,Bustamante, Juan,Abd Elmageed, Zakaria Y.,Ali, Hamed I.
, p. 31 - 52 (2018/04/26)
Protein kinases are promising therapeutic targets for cancer therapy. Here, we applied multiple approaches to optimize the potency and selectivity of our reported alloxazine scaffold. Flexible moieties at position 2 of the hetero-tricyclic system were inc
SUBSTITUTED SULFONAMIDE COMPOUNDS
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Page/Page column 45-46; 48, (2008/12/06)
Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.