4-[(4-Methyl-1-piperazinyl)methyl]benzylamine

Base Information

• Chemical Name: 4-[(4-Methyl-1-piperazinyl)methyl]benzylamine
• CAS No.: 515162-20-6
• Molecular Formula: C13H21N3
• Molecular Weight: 219.33
• Hs Code.: 2933599090
• European Community (EC) Number: 633-428-7
• DSSTox Substance ID: DTXSID80428763
• Nikkaji Number: J3.238.158H
• Wikidata: Q82241584
• Mol file: 515162-20-6.mol

Synonyms:515162-20-6;4-[(4-Methyl-1-piperazinyl)methyl]benzylamine;[4-[(4-methylpiperazin-1-yl)methyl]phenyl]methanamine;(4-((4-methylpiperazin-1-yl)methyl)phenyl)methanamine;(4-[(4-Methylpiperazin-1-yl)methyl]phenyl)methylamine;{4-[(4-Methylpiperazin-1-yl)methyl]phenyl}methylamine;{4-[(4-methylpiperazin-1-yl)methyl]phenyl}methanamine;[4-[(4-METHYLPIPERAZIN-1-YL)METHYL]PHENYL]METHYLAMINE;Benzenemethanamine,4-[(4-methyl-1-piperazinyl)methyl]-;SCHEMBL111367;1-{4-[(4-methylpiperazin-1-yl)methyl]phenyl}methanamine;DTXSID80428763;HILINUGDTTXRNZ-UHFFFAOYSA-N;MFCD08060530;AKOS000125625;4-(4-Methylpiperazinomethyl)benzylamine;TS-01513;CS-0206270;EN300-40879;F78837;4-[(4-Methyl-1-piperazinyl)methyl]benzylamine, 97%;{4-[(4-Methylpiperazin-1-yl)-methyl]phenyl}methylamine

Chemical Property of 4-[(4-Methyl-1-piperazinyl)methyl]benzylamine

Chemical Property:

• Vapor Pressure: 0.000112mmHg at 25°C
• Refractive Index: n20/D 1.547
• Boiling Point: 336.5 °C at 760 mmHg
• Flash Point: 155.1 °C
• PSA: 32.50000
• Density: 1.06 g/cm³
• LogP: 1.46880
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 219.173547683
• Heavy Atom Count: 16
• Complexity: 191

Purity/Quality:

98%,99%, ^*data from raw suppliers

{4-[(4-Methylpiperazin-1-yl)methyl]phenyl}methylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C,Xi
• Hazard Codes: C,Xi
• Statements: 37/38-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CCN(CC1)CC2=CC=C(C=C2)CN

Technology Process of 4-[(4-Methyl-1-piperazinyl)methyl]benzylamine

There total 4 articles about 4-[(4-Methyl-1-piperazinyl)methyl]benzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.5%

4-[(4-methyl-1-piperazinyl)methyl]benzonitrile (125743-63-7) → (4-((4-methylpiperazin-1-yl)methyl)phenyl)methanamine (515162-20-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 3h; Cooling with ice;

Reference yield:

4-cyanobenzyl bromide (17201-43-3) → (4-((4-methylpiperazin-1-yl)methyl)phenyl)methanamine (515162-20-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium carbonate / N,N-dimethyl-formamide / 20 - 90 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 25 °C / Inert atmosphere

With lithium aluminium tetrahydride; sodium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.ejmech.2018.04.029

Reference yield:

1-methyl-piperazine (109-01-3) → (4-((4-methylpiperazin-1-yl)methyl)phenyl)methanamine (515162-20-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium carbonate / N,N-dimethyl-formamide / 20 - 90 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 25 °C / Inert atmosphere

With lithium aluminium tetrahydride; sodium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.ejmech.2018.04.029

upstream raw materials:

4-cyanobenzyl bromide

1-methyl-piperazine

4-[(4-methyl-1-piperazinyl)methyl]benzonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 515162-20-6 [4-[(4-METHYLPIPERAZIN-1-YL)METHYL]PHENYL]METHYLAMINE

Send

Send

Metric Ton KG G Pound L ML

Send

Send