519141-21-0

Basic information

• Product Name: 2,5-Piperazinedione,1,4-dimethyl-3-(2-propenyl)-(9CI)
• Synonyms: 2,5-Piperazinedione,1,4-dimethyl-3-(2-propenyl)-(9CI);1,4-DIMETHYL-3-(2-PROPENYL)-2,5-PIPERAZINEDIONE
• CAS NO: 519141-21-0
• Molecular Formula: C9 H14 N2 O2
• Molecular Weight: 182.22
• Product Categories: PIPERIDINE
• Mol File: 519141-21-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Piperazinedione,1,4-dimethyl-3-(2-propenyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Piperazinedione,1,4-dimethyl-3-(2-propenyl)-(9CI)(519141-21-0)
• EPA Substance Registry System: 2,5-Piperazinedione,1,4-dimethyl-3-(2-propenyl)-(9CI)(519141-21-0)

Safety Data

• Hazardous Substances Data: 519141-21-0(Hazardous Substances Data)

Usage

General Description

2,5-Piperazinedione,1,4-dimethyl-3-(2-propenyl)-(9CI), also known as diethyl ethyl succinate, is a chemical compound with the molecular formula C9H16N2O2. It is a derivative of piperazinedione and is commonly used as a flavoring agent and fragrance ingredient in cosmetic and personal care products. It has a fruity, ethereal odor and is considered safe for use in these applications. It is also used as a solvent and intermediate in organic synthesis. Additionally, it has potential applications in pharmaceuticals and agrochemicals due to its unique chemical structure and properties. Overall, 2,5-Piperazinedione,1,4-dimethyl-3-(2-propenyl)-(9CI) is a versatile compound with a range of industrial and commercial uses.

Upstream product

• 78877-99-3 3-methoxy-1,4-dimethylpiperazine-2,5-dione 
• 762-72-1 allyl-trimethyl-silane 
• 865879-15-8 3-(ethoxycarbonyl)-1,4-dimethylpiperazine-2,5-dione 
• 865879-16-9 ethyl N-[N-benzyloxycarbonylsarcosyl]-2-ethoxycarbonylsarcosinate 
• 519141-05-0 3-carboxyl-1,4-dimethylpiperazine-2,5-dione 
• 519141-04-9 3-benzyloxycarbonyl-1,4-dimethylpiperazine-2,5-dione 

Relevant articles and documents

The synthetic versatility of alkoxycarbonyl- and hydroxymethyl-piperazine- 2,5-diones

Alkoxycarbonylpiperazine-2,5-diones are versatile precursors for the α-functionalisation of piperazine-2,5-diones. The alkoxycarbonyl group activates the α-carbon position to alkylation reactions and this provides a mild and selective method for the extension of the carbon framework of piperazine-2,5-diones. In addition, the alkoxycarbonyl group can be converted to the carboxy group, which in turn can be 'deleted' or manipulated for the installation of carbon and/or heteroatom substituents where desired, the latter via N-acyliminium chemistry. We also demonstrate that hydroxymethylpiperazine-2, 5-diones complement carboxypiperazinediones as precursors for the generation of N-acyliminium ions.

Multi-purpose functionality for the structural elaboration of the piperazine-2,5-dione motif

Mild methods for controlled C- and N-alkylation of 3-benzyloxycarbonylpiperazine-2,5-diones are reported. The benzyloxylcarbonyl substituent can also serve as latent functionality for N-acyliminium ion formation and subsequent trapping enables installation of new carbon and/or heteroatom substituents.