519186-18-6Relevant academic research and scientific papers
Antibacterial nicotinamide adenine dinucleotide synthetase inhibitors: Amide- and ether-linked tethered dimers with α-amino acid end groups
Velu, Sadanandan E.,Mou, Liyuan,Luan, Chi-Hao,Yang, Zhengrong W.,DeLucas, Lawrence J.,Brouillette, Christie G.,Brouillette, Wayne J.
, p. 2612 - 2621 (2008/02/04)
Tethered dimers incorporating natural α-amino acid end groups were synthesized, including examples in which the previously reported esterase-sensitive ester linker was replaced with more stable amide or ether linkers. These compounds remained effective both as inhibitors of NAD synthetase and as potent antibacterial agents for Gram-positive strains. Studies on nonspecific effects, including detergent properties and promiscuous inhibition, suggested little contribution to observed activities.
Synthesis of New Mesomorphic Polyesters by Polymerization of Bifunctional Monomers
Keller, Patrick
, p. 247 - 256 (2007/10/02)
New polyesters have been synthesized by high temperature polycondensation of bifunctional monomers (4-(ω-(4-acetyloxyphenyloxy)alkyloxy)benzoic acids).Their mesomorphic porperties have been studied.By analogy with the chemistry of polypeptide polymers (us
