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2-Amino-4-chlorothiazole is a chemical compound characterized by the molecular formula C3H3ClN2S. It is a thiazole derivative featuring a chlorine substituent at the 4-position and an amino group at the 2-position. 2-Amino-4-chlorothiazole is recognized for its role as an intermediate in the synthesis of various products, including pharmaceuticals, agrochemicals, and organic compounds. Additionally, it is utilized in the preparation of dyes and serves as a building block in organic synthesis, highlighting its versatility as a reagent in a broad spectrum of chemical reactions.

52107-46-7

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52107-46-7 Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-4-chlorothiazole is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Amino-4-chlorothiazole is employed as an intermediate in the production of agrochemicals, aiding in the creation of compounds that can enhance crop protection and yield.
Used in Dye Preparation:
2-Amino-4-chlorothiazole is used as a component in the preparation of dyes, capitalizing on its chemical properties to produce a range of colorants for various applications.
Used in Organic Synthesis:
As a building block in organic synthesis, 2-Amino-4-chlorothiazole is utilized for its versatility, allowing chemists to construct a wide array of organic compounds through various chemical reactions.

Check Digit Verification of cas no

The CAS Registry Mumber 52107-46-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,1,0 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 52107-46:
(7*5)+(6*2)+(5*1)+(4*0)+(3*7)+(2*4)+(1*6)=87
87 % 10 = 7
So 52107-46-7 is a valid CAS Registry Number.
InChI:InChI=1/C3H3ClN2S/c4-2-1-7-3(5)6-2/h1H,(H2,5,6)

52107-46-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-1,3-thiazol-2-amine

1.2 Other means of identification

Product number -
Other names 4-chlorothiazol-2-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52107-46-7 SDS

52107-46-7Relevant articles and documents

STK4 INHIBITORS FOR TREATMENT OF HEMATOLOGIC MALIGNANCIES

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Paragraph 00827, (2017/01/09)

The application relates to compounds of Formula (I'): which modulate the activity of a kinase (e.g., STK4), a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease or disorder associated with the modulation of a kinase, such as STK4.

Story of an Age-Old Reagent: An Electrophilic Chlorination of Arenes and Heterocycles by 1-Chloro-1,2-benziodoxol-3-one

Wang, Mengzhou,Zhang, Yanyan,Wang, Tao,Wang, Chao,Xue, Dong,Xiao, Jianliang

supporting information, p. 1976 - 1979 (2016/06/01)

By the use of 1-chloro-1,2-benziodoxol-3-one, an age-old reagent, the practical and efficient chlorination method is achieved. This hypervalent iodine reagent is amenable not only to the chlorination of nitrogen-containing heterocycles but also to selected classes of arenes, BODIPY dyes, and pharmaceuticals. In addition, the advantages, such as easy preparation and recyclable, air- and moisture-stable, in combination with the success in a gram-scale experiment grant this reagent great potential for industrial application.

Naphthyridin derivatives

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Page/Page column 31, (2008/06/13)

The present invention relates to heterocyclic derivatives of formula I wherein R1, R2 and R3 are as defined in the description and claims, which compounds are metabotropic glutamate receptor 5 antagonists.

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