- Constrained phytoestrogens and analogues as ERβ selective ligands
-
A new series of ERbeta (ERβ) selective ligands has been prepared. One of the compounds 6, structurally related to the phytoestrogen apigenin 4, displays a binding preference for ERβ over ERα of over 40-fold. In addition to its binding selectivity, 6 was a
- Miller, Chris P.,Collini, Michael D.,Harris, Heather A.
-
p. 2399 - 2403
(2007/10/03)
-
- Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents
-
This invention provides estrogen receptor modulators of formula 1, having the structure wherein X, Y1, Y2, Y3, Y4, Z1, Z2, Z3, and Z4 are as defined in the specificati
- -
-
-