- Novel synthetic method of halogenated aromatic hydrocarbon
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The invention discloses a novel synthetic method of halogenated aromatic hydrocarbon, wherein p-chlorotoluene is used as a raw material, copper chloride or cuprous chloride is used as a catalyst, andp-chlorobenzotrifluoride is synthesized through two steps of chlorination and fluorination. Compared with the method in the prior art, the method of the invention has the following characteristics that raw materials are subjected to heating dehydration treatment in a dehydration kettle, so that the chlorination side reactions are few, the product purity is high, the grading chlorination device does not need to be additionally arranged, the technological process is simple, and the operation is convenient; and by adding the catalyst in batches in the chlorination process, the use efficiency of the catalyst is improved, so that the emission of the byproducts and the waste gas generated by the chlorination reaction in production is greatly reduced, and the emission of pollutants in the production process is reduced.
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Paragraph 0017; 0021; 0025; 0029
(2020/01/25)
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- Novel fluorination process of p-chlorobenzotrifluoride
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The invention discloses a novel fluorination process of p-chlorobenzotrifluoride. P-chlorotoluene is used as a raw material, and 4-chlorobenzotrifluoride is synthesized through two steps of chlorination and fluorination. Compared with the prior art, the fluorination process has the advantages of no catalyst, lower cost than other organic catalysts or noble metal catalysts, convenience in recoveryand no pollution to the environment; a solvent-free fluorination process is adopted, so that the emission of by-products and waste gas of a solvation reaction is greatly reduced, and the emission of pollutants in the production process is reduced.
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Paragraph 0014; 0016
(2019/12/02)
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- Synthesis method of 4-chlorobenzotrifluoride
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The invention discloses a synthetic method of 4-chlorobenzotrifluoride. P-chlorotoluene is used as a raw material, and 4-chlorobenzotrifluoride is synthesized through two steps of chlorination and fluorination. Compared with the prior art, the raw materials are subjected to heating dehydration treatment in the dehydration kettle, chlorination side reactions are few, the product purity is high, a graded chlorination device does not need to be added, the technological process is simple, and operation is convenient; according to the chlorination process, a mode of adding the catalyst in batches is adopted, so that the use efficiency of the catalyst is improved, the emission of byproducts and waste gas generated by chlorination reaction in production is greatly reduced, and the emission of pollutants in the production process is reduced.
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Paragraph 0020; 0024; 0028; 0032
(2019/12/02)
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- CLEAN PROCESS FOR PREPARING CHLOROFORMYL-SUBSTITUTED BENZENE
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Clean process for preparing a chloroformyl-substituted benzene by oxidation of a tail gas hydrogen chloride from a chlorination reaction and a chloroacylation reaction and recycling of the resulting oxidation product chlorine gas into the chlorination reaction. The present invention provides a clean process for preparing a polymer-grade chloroformyl-substituted benzene.
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Paragraph 0125; 0139; 0150; 0163
(2017/12/17)
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- PhPOCl2as a potent catalyst for chlorination reaction of phenols with PCl5
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Phenols are easily converted to the corresponding aryl chlorides by using phosphorus pentachloride (PCl5) and a catalytic amount of phenylphosphonic dichloride (PhPOCl2), which is a new efficient method for synthesis of aryl chloride in good yields.
- Wu, Jiang,Zhou, Junpeng,Shi, Yalei,Zhu, Jintao
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supporting information
p. 1619 - 1624
(2016/10/09)
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- METHOD FOR THE PREPARATION OF TRICHLOROMETHYL-GROUP-SUBSTITUTED BENZENE
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The present application relates to a method for photochlorination, and specifically to photochlorination by a photochemical reaction of an aromatic compound with gaseous chlorine so as to prepare a trichloromethyl-substituted benzene, and to a method using bis-(trichloromethyl)-benzene as the trichloromethyl-substituted benzene to prepare by further reaction bis-(chloroformyl)-benzene. Through the control of temperature, illuminance and consumption of gaseous chlorine, the method of this application can greatly improve the purity of trichloromethyl-substituted benzene and further prepare polymer-grade bis-(chloroformyl)-benzene with low cost. The present application also relates to a method for purifying trichloromethyl-substituted benzene, and specifically to a method for purifying trichloromethyl-substituted benzene via molecular distillation. The present application further relates to a photochlorination reactor for use in photochlorination reactions (such as those of the present application).
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Paragraph 0156
(2016/06/28)
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- PROCESS FOR THE PREPARATION OF 2,6-DIHALO-PARA-TRIFLUOROMETHYL- ANILINES AS INTERMEDIATES OF PYRAZOLES
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The present invention provides a process for the preparation of 2,6-dihalo-para-trifluoromethylanilines as intermediates for pyrazoles comprising the halogenation of para-trifluoromethylaniniline with dihalogen.
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Page/Page column 7
(2015/09/23)
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- Process for the preparation of nuclear-halogenated benzotrichlorides from the corresponding benzotrifluorides
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Nuclear-halogenated benzotrichlorides are prepared in a particularly advantageous manner from the corresponding nuclear-halogenated benzotrifluorides by reacting nuclear-halogenated benzotrifluorides with silicon tetrachloride in the presence of catalytic amounts of aluminium trichloride.
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- Phosporylation of 1,3-di(N-alkyl)azoles by phosphorus(V) acid chlorides - A route to potential haptens derived from phosphinic acids
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Phosphorylation of N-alkylated imidazoles and benzimidazoles at C-2 by CH3POCl2, PhPOCl2, POCl3 in pyridine-triethylamine solution is described. The formed heteroaryl-substituted phosphinic or phosphonic acid chlorides were transformed without isolation into the corresponding phosphinic (phosphinic) acids, their salts or amides with moderate yields. This reaction opens a simple way to potential haptens derived from phosphinic acids. These haptens mimic tetrahedral transition state of many reactions and can be used to obtain catalytic antibodies. The functionalized heteroarylsubstituted phosphinic acids which have been used as hapten precursors were obtained by phosphorylation of 1-alkyl-5-nitrobenzimidazole or by usage of a new phosphorylating reagent - (4-trichloromethylphenyl)phosphonic dichloride.
- Komarov,Kornilov,Turov,Gorichko,Popov,Tolmachev,Kirby
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p. 12417 - 12424
(2007/10/02)
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- α-Chlorination process
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A process for α-chlorination of side chains of electronegatively substituted aromatic compounds with dichlorine monoxide.
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