52414-99-0 Usage
Nitroaromatic compound
A type of aromatic organic compound containing a nitro group (-NO2) bonded to a benzene ring.
Benzene ring
A six-membered unsaturated hydrocarbon ring with alternating single and double carbon-carbon bonds in a planar hexagonal structure.
Methyl group at the 3-position
A carbon atom bonded to three hydrogen atoms (-CH3) attached to the third carbon of the benzene ring.
Iodo group at the 1-position
A single iodine atom (-I) attached to the first carbon of the benzene ring.
Nitro group at the 2-position
A functional group consisting of an oxygen atom double-bonded to two nitrogen atoms (-NO2) attached to the second carbon of the benzene ring.
Organic synthesis
A chemical process used to create new organic compounds by forming or breaking chemical bonds.
Precursor
A starting material used in a chemical reaction to produce a desired product.
Pharmaceuticals
Medications or drugs used in the treatment, cure, prevention, or diagnosis of diseases or medical conditions.
Agrochemicals
Chemical products used in agriculture to protect crops from pests, diseases, and weeds, and to improve crop yield and quality.
Reagent
A chemical substance used in chemical research or analysis to test, detect, or produce other substances.
Intermediate
A temporary compound formed during a chemical reaction, which can be further transformed into the final product.
Toxic
Having harmful effects on living organisms, especially when ingested, inhaled, or in contact with the skin.
Proper precautions
Necessary safety measures taken to minimize the risk of exposure to hazardous substances, including the use of personal protective equipment and following safety guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 52414-99-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,1 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 52414-99:
(7*5)+(6*2)+(5*4)+(4*1)+(3*4)+(2*9)+(1*9)=110
110 % 10 = 0
So 52414-99-0 is a valid CAS Registry Number.
52414-99-0Relevant articles and documents
Rhodium-catalysed: Ortho -alkynylation of nitroarenes
Echavarren, Antonio M.,García-Morales, Cristina,Mayans, Joan Guillem,Montesinos-Magraner, Marc,Tan, Eric
, p. 14731 - 14739 (2021/12/02)
The ortho-alkynylation of nitro-(hetero)arenes takes place in the presence of a Rh(iii) catalyst to deliver a wide variety of alkynylated nitroarenes regioselectively. These interesting products could be further derivatized by selective reduction of the nitro group or palladium-catalysed couplings. Experimental and computational mechanistic studies demonstrate that the reaction proceeds via a turnover-limiting electrophilic C-H metalation ortho to the strongly electron-withdrawing nitro group. This journal is
Decarboxylative Halogenation and Cyanation of Electron-Deficient Aryl Carboxylic Acids via Cu Mediator as Well as Electron-Rich Ones through Pd Catalyst under Aerobic Conditions
Fu, Zhengjiang,Li, Zhaojie,Song, Yuanyuan,Yang, Ruchun,Liu, Yanzhu,Cai, Hu
, p. 2794 - 2803 (2016/04/26)
Simple strategies for decarboxylative functionalizations of electron-deficient benzoic acids via using Cu(I) as promoter and electron-rich ones by employing Pd(II) as catalyst under aerobic conditions have been established, which lead to smooth synthesis of aryl halides (-I, Br, and Cl) through the decarboxylative functionalization of benzoic acids with readily available halogen sources CuX (X = I, Br, Cl), and easy preparation of benzonitriles from decarboxylative cyanation of aryl carboxylic acids with nontoxic and low-cost K4Fe(CN)6 under an oxygen atmosphere for the first time.
Palladium-catalyzed synthesis of 1,2-dihydro-4(3H)-carbazolones. Formal total synthesis of murrayaquinone A
Scott, Tricia L.,S?derberg, Bj?rn C. G.
, p. 6323 - 6332 (2007/10/03)
Two sequential palladium-catalyzed reactions are the key steps in a novel synthetic route to 1,2-dihydro-4(3H)-carbazolones. The steps are an intermolecular Stille cross-coupling followed by a reductive N-heteroannulation. A formal total synthesis of murrayaquinone A, employing this sequence, is reported.
