cas 526-02-3, 4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]piperidine-2,6-dione | Articles data ｜lookchem

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526-02-3

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Synthesis and antiviral activities of synthetic glutarimide derivatives
A series of novel glutarimide compounds were synthesized and their antiviral activities were evaluated. The compounds displaying the strongest antiviral activities included 5, 6f, 7e and 9 against coxsackievirus B3 (Cox B3), 10 and 6f against influenza vi
Ji, Xing-Yue,Zhong, Zhao-Jin,Xue, Si-Tu,Meng, Shuai,He, Wei-Ying,Gao, Rong-Mei,Li, Yu-Huan,Li, Zhuo-Rong
experimental part
p. 1436 - 1441
(2010/12/25)

Synthesis of actiketal, a glutarimide antibiotic
The first synthesis of actiketal (RK-441S), an antibiotic from Streptomyces pulveraceus subsp. epiderstagenes, was achieved from 5,7- dimethylbenzofuran and dimethyl glutaconate via palladium-assisted coupling reaction as a key step. (C) 2000 Elsevier Science Ltd.
Kiyota, Hiromasa,Shimizu, Yuko,Oritani, Takayuki
p. 5887 - 5890
(2007/10/03)

SYNTHESIS OF ACTIPHENOL AND ITS NORMETHYL ANALOGUES AND 6-HYDROXY DERIVATIVES
The synthesis has been achieved of the natural antibiotic actiphenol and its 4,6-bisnormethyl and 4,5-bisnormethyl-5-methyl analogues and also its 6-hydroxy derivatives, starting from 2-(β-glutarimidyl-acetyl)cyclohexane-1,3-diones.
Lakhvich, F. A.,Buravskaya, T. N.,Akhrem, A. A.
p. 526 - 529
(2007/10/02)

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Chemical Properties

Melting Point: 200-202°
Boiling Point: 498.7°Cat760mmHg
Flash Point:255.4°C
Density: 1.232g/cm³
Storage Temp.:?20°C
Vapor Pressure: 1.44E-10mmHg at 25°C
PSA: 83.47000
LogP: 1.96340

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