526-02-3

Usage

Uses

Used in Pharmaceutical Industry:
4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]piperidine-2,6-dione is used as a building block for the development of new drugs due to its unique structure and functional groups, which can be utilized in the synthesis of pharmacologically active compounds.
Used in Organic Synthesis:
In the field of organic synthesis, 4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]piperidine-2,6-dione serves as a versatile precursor, enabling the creation of a wide range of chemical entities for various applications.

InChI:InChI=1/C15H17NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h3-4,10,20H,5-7H2,1-2H3,(H,16,18,19)

Upstream product

• 170807-02-0 4-[2-(2-Chloro-3,5-dimethyl-6-oxo-cyclohex-1-enyl)-2-oxo-ethyl]-piperidine-2,6-dione 
• 66-81-9 Cycloheximide 
• 845-48-7 2,4-dimethylphenyl(2,6-dioxopiperidin-4-yl)acetate 

Downstream Products

• 1267513-08-5 4-[2-hydroxy-2-(2-hydroxy-3,5-dimethylphenyl)ethyl]piperidin-2,6-dione 
• 1154-58-1 dehydrocycloheximide 

Relevant academic research and scientific papers

Synthesis and antiviral activities of synthetic glutarimide derivatives

A series of novel glutarimide compounds were synthesized and their antiviral activities were evaluated. The compounds displaying the strongest antiviral activities included 5, 6f, 7e and 9 against coxsackievirus B3 (Cox B3), 10 and 6f against influenza vi

Synthesis of actiketal, a glutarimide antibiotic

The first synthesis of actiketal (RK-441S), an antibiotic from Streptomyces pulveraceus subsp. epiderstagenes, was achieved from 5,7- dimethylbenzofuran and dimethyl glutaconate via palladium-assisted coupling reaction as a key step. (C) 2000 Elsevier Science Ltd.

SYNTHESIS OF ACTIPHENOL AND ITS NORMETHYL ANALOGUES AND 6-HYDROXY DERIVATIVES

The synthesis has been achieved of the natural antibiotic actiphenol and its 4,6-bisnormethyl and 4,5-bisnormethyl-5-methyl analogues and also its 6-hydroxy derivatives, starting from 2-(β-glutarimidyl-acetyl)cyclohexane-1,3-diones.