53180-92-0

Basic information

• Product Name: 5-AMINO-4-CHLOROPYRIDAZINE
• Synonyms: 5-AMINO-4-CHLOROPYRIDAZINE;5-chloropyridazin-4-aMine;5-AMaino-4-chloropyridazine;4-Amino-5-chloropyridazine
• CAS NO: 53180-92-0
• Molecular Formula: C₄H₄ClN₃
• Molecular Weight: 129.55
• Mol File: 53180-92-0.mol

Chemical Properties

• Melting Point: 70-73 °C(Solv: benzene (71-43-2))
• Boiling Point: 326.9±22.0 °C(Predicted)
• Appearance: /
• Density: 1.437±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 4.50±0.10(Predicted)
• CAS DataBase Reference: 5-AMINO-4-CHLOROPYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-4-CHLOROPYRIDAZINE(53180-92-0)
• EPA Substance Registry System: 5-AMINO-4-CHLOROPYRIDAZINE(53180-92-0)

Safety Data

• Hazardous Substances Data: 53180-92-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Amino-4-chloropyridazine is used as a key intermediate in the synthesis of various drugs. Its unique structure allows for the development of new pharmaceutical compounds with potential therapeutic applications, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Amino-4-chloropyridazine serves as a crucial building block for the production of pesticides. Its incorporation into these chemical products aids in the development of more effective and targeted pest control solutions, enhancing agricultural productivity and crop protection.
Used in Organic Chemistry Research:
5-Amino-4-chloropyridazine is also of significant interest to researchers in the field of organic chemistry. Its unique structure and reactivity provide opportunities for exploring new chemical reactions and mechanisms, furthering the understanding of heterocyclic chemistry and its applications.

Upstream product

• 20744-39-2 4-aminopyridazine 

Downstream Products

• 1466574-75-3 5-(4-fluoro-2-methoxyphenyl)pyridazin-4-ylamine 

Relevant articles and documents

Synthesis method of 5-chloro-4-aminopyridazine

The invention relates to the technical field of chemical synthesis, and concretely discloses a synthesis method of 5-chloro-4-aminopyridazine. The synthesis method comprises the following steps: 3,6-dichloro-4-aminopyridazine used as an initial raw material undergoes hydrodechlorination to obtain a 4-aminopyridazine key intermediate at a high yield, and then the key intermediate is chlorinated with N-chlorosuccinimide (NCS) to obtain the target product 5-chloro-4-aminopyridazine. The 5-chloro-4-aminopyridazine is a key intermediate for drug synthesis, but the synthesis route of 5-chloro-4-aminopyridazine, especially the synthesis route suitable for commercial mass production, is not reported. The synthesis method of the target compound is provided for the first time, is particularly suitable for commercial mass production, and allows the 5-chloro-4-aminopyridazine to be prepared with high yield and high purity.