53318-09-5Relevant articles and documents
Synthesis of gingerol and diarylheptanoids
Sabitha, Gowravaram,Srinivas, Chitti,Reddy, Teega Rammohan,Yadagiri, Kurra,Yadav, Jhillu Singh
, p. 2124 - 2133 (2012/03/27)
The synthesis of gingerol 1 and related compounds 2-5 along with diarylheptanoids 6-8 has been accomplished using a Keck allylation, Crimmins' aldol reaction, aldehyde coupling with acetylene, and chelation controlled reductions as the key reactions. The absolute configuration of these molecules was confirmed by preparing their acetonide derivatives and by comparison of the NMR data with natural compounds.
A new method for the demetallation of tricarbonyliron diene complexes by total hydrogenation with Raney nickel. Application to a very short synthesis of (+)-[6]-gingerdiol
Franck-Neumann, Michel,Geoffroy, Philippe,Bissinger, Paul,Adelaide, Sylvie
, p. 6401 - 6404 (2007/10/03)
Demetallation of tricarbonyliron diene complexes is rapidly achieved by treatment with freshly prepared Raney nickel. The ligands which are totally hydrogenated during the decomplexation are easily isolated in high yields, without racemization, if chiral.
GINGERDIOL RELATED COMPOUNDS FROM THE RHIZOMES OF ZINGIBER OFFICINALE
Kikuzaki, Hiroe,Tsai, Saiu-Mei,Nakatani, Nobuji
, p. 1783 - 1786 (2007/10/02)
-Gingerdiol and four analogues, (3R,5S)-5-acetoxy-3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decane, (3R,5S)-3-acetoxy-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decane, (3R,5S)-3,5-diacetoxy-1-(4-hydroxy-3-methoxyphenyl)decane and (3R,5S)-3,5-diacetoxy-1-(3,4