- Asymmetric Cycloisomerization of o-Alkenyl-N-Methylanilines to Indolines by Iridium-Catalyzed C(sp3)?H Addition to Carbon–Carbon Double Bonds
-
Highly enantioselective cycloisomerization of N-methylanilines, bearing o-alkenyl groups, into indolines is established. An iridium catalyst bearing a bidentate chiral diphosphine effectively promotes the intramolecular addition of the C(sp3)?H bond across a carbon–carbon double bond in a highly enantioselective fashion. The reaction gives indolines bearing a quaternary stereogenic carbon center at the 3-position. The reaction mechanism involves rate-determining oxidative addition of the N-methyl C?H bond, followed by intramolecular carboiridation and subsequent reductive elimination.
- Torigoe, Takeru,Ohmura, Toshimichi,Suginome, Michinori
-
p. 14272 - 14276
(2017/10/23)
-
- COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS
-
The disclosure provides Group 6 complexes, which, in some embodiments, are useful for catalyzing olefin metathesis reactions. In some embodiments, the compounds are compounds of the following formula (I) wherein: M is a Group 6 metal atom; X is an oxygen
- -
-
Page/Page column 51
(2015/11/18)
-
- Chemo-, Regio-, and stereoselective trifluoromethylation of styrenes via visible light-driven single-electron transfer (SET) and triplet-triplet energy transfer (TTET) processes
-
A process for tunable and chemo-, regio-, and stereoselective photocatalytic trifluoromethylation of styrenes was developed. Thermodynamically stable E-trifluoromethylated alkenes were prepared using Tognis reagent in the presence of Ru(bpy)3Cl2·6H2O under visible light irradiation, whereas less thermodynamically stable Z-trifluoromethylated alkenes were obtained by employing Umemotos reagent and photocatalyst Ir(ppy)3.
- Lin, Qing-Yu,Xu, Xiu-Hua,Qing, Feng-Ling
-
p. 10434 - 10446
(2015/02/19)
-
- Efficient cyclization of tertiary amines and alkenes promoted by KOt-Bu-DMF
-
Nitrogen heterocycles could be prepared in good yields via intramolecular cyclization of tertiary amines and alkenes promoted by KOt-Bu-DMF. This journal is The Royal Society of Chemistry 2013.
- Chen, Yan-Yan,Zhang, Xue-Jing,Yuan, Hui-Min,Wei, Wen-Tao,Yan, Ming
-
supporting information
p. 10974 - 10976
(2013/11/19)
-
- Vinylation of aryl bromides using an inexpensive vinylpolysiloxane
-
(Chemical Equation Presented) A mild and general method for the palladium-catalyzed vinylation of aryl bromides has been developed. The use of tetrabutylammonium fluoride (TBAF) as the activator and an inexpensive and nontoxic vinyl donor, 1,3,5,7-tetramethyl-1,3,5,7-tetravinylcyclotetrasiloxane (D4V, 1), allows for a general and high-yielding preparation of substituted styrenes.
- Denmark, Scott E.,Butler, Christopher R.
-
-