534603-26-4Relevant articles and documents
ENANTIOPURE HETEROCYCLIC COMPOUND USEFUL FOR THE PREPARATION OF PEPTIDES WHICH CAN BE POTENTIALLY USED AS MEDICAMENTS
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Page/Page column 17, (2008/06/13)
Enantiopure heterocyclic compound Enantiopure heterocyclic compound of formula (I) in which J is chosen from C, N, O and S; Z is H or a group for protecting the amino functional group, R3 denotes H or an organic residue, m is 0, 1 or 2 and n is 0, 1 or 2, and in which the heterocycle is preferably substituted with at least one substituent other than CH2-COOR3.
The synthesis of 2-ketopiperazine acetic acid esters and amides from ethylenediamines with maleates and maleimides
Abelman, Matthew M.,Fisher, Karl J.,Doerffler, Edward M.,Edwards, Paul J.
, p. 1823 - 1826 (2007/10/03)
The reaction of substituted ethylenediamines with various fumarates, maleates, and maleimides to form substituted ketopiperazine acetic acid esters and amides was investigated. This method affords a straightforward, high yield approach to a variety of potential peptidomimetics and can yield surprising results with regard to regio- and stereoselectivity.