53596-81-9

Basic information

• Product Name: 8-Bromooctan-1-ol acetate
• Synonyms: 8-Bromooctan-1-ol acetate;8-broMo-1-octanol acetate;8-Bromooctyl acetate
• CAS NO: 53596-81-9
• Molecular Formula: C₁₀H₁₉BrO₂
• Molecular Weight: 251.16066
• Mol File: 53596-81-9.mol

Chemical Properties

• Boiling Point: 149-159 °C(Press: 15-16 Torr)
• Appearance: /
• Density: 1.194±0.06 g/cm3 (20 ºC 760 Torr)
• CAS DataBase Reference: 8-Bromooctan-1-ol acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Bromooctan-1-ol acetate(53596-81-9)
• EPA Substance Registry System: 8-Bromooctan-1-ol acetate(53596-81-9)

Safety Data

• Hazardous Substances Data: 53596-81-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
8-Bromooctan-1-ol acetate is used as an intermediate in various chemical reactions for the synthesis of different organic compounds. Its unique structure allows it to be a valuable building block in the creation of more complex molecules.
Used in Pharmaceutical Industry:
8-Bromooctan-1-ol acetate is used as a starting material for the synthesis of pharmaceutical compounds. Its reactivity and structural properties make it a useful precursor in the development of new drugs and therapeutic agents.
Used in Chemical Research:
8-Bromooctan-1-ol acetate is used as a research tool in the study of chemical reactions and mechanisms. Its properties and reactivity can provide insights into the behavior of similar compounds and contribute to the understanding of organic chemistry.
Used in Material Science:
8-Bromooctan-1-ol acetate is used in the development of new materials with specific properties. Its unique structure and reactivity can be exploited to create materials with tailored characteristics for various applications, such as in electronics or coatings.

Upstream product

• 50816-19-8 8-bromooctanol 
• 108-24-7 acetic anhydride 
• 22352-19-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl-(1->4)-2,3,6-tri-O-acetyl-β-D-glucopyranosyl acetate 
• 604-69-3 β-D-glucose pentaacetate 
• 4163-60-4 β-D-galactose peracetate 
• 75-36-5 acetyl chloride 
• 629-41-4 1,8-Octanediol 

Downstream Products

• 77328-78-0 (8-Acetoxyoctyl)-triphenylphosphonium-bromid 
• 231943-23-0 3-dimethylamino-benzoic acid 8-(5-nitro-indol-1-yl)-octyl ester 
• 807639-76-5 benzaldehyde,4-chloro-2-nitro-, O-[8-(acetyloxy)octyl]oxime 
• 1056010-65-1 1-octanol, 8-(3-nitrophenoxy)-, acetate (ester) 
• 807639-47-0 1-octanol,8-(4-chloro-2-nitrophenoxy)-,acetate(ester) 
• 807639-81-2 6-quinazolinol, 4-[[3-[(8-hydroxyoctyl)oxy]phenyl]amino]-7-methoxy- 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE

Disclosed are compounds and compositions for inhibiting the expression of a pattern recognition receptor (e.g., STING), and methods of use thereof.

Synthesis method of (Z/E)-8-dodecen-1-alcohol acetate compound

The invention provides a synthesis method of a (Z/E)-8-dodecane-1-alcohol acetate compound. Specifically, the method includes the following steps: preparing 8-bromooctanol from 1,8-octanediol, then performing esterification reaction to obtain 8-Bromooctanol acetate, and then preparing omega-acetoxyoctanyl triphenyl phosphine bromide salt, and finally performing reaction through Scholoer-wittig toobtain (Z/E)-8-dodecene-1-alcohol acetate. The synthesis method has the advantages of high availability of raw materials, high yield and good selectivity, and is suitable for industrial production.

Facile synthesis of 3-(ω-acetoxyalkyl)thiophenes and derived copolythiophenes using Rieke zinc

An optimized synthetic protocol toward highly reactive Rieke zinc is applied for the preparation of a series of ω-(2,5-dibromothiophene-3-yl) alkyl acetate monomers and statistical copolythiophenes derived thereof, with 10% of ester-functionalized side chains. The obtained conjugated polymers are attractive electron donor materials for organic solar cells, notably to increase the thermodynamic stability of the bulk heterojunction polymer:fullerene active layer blend, and are fully characterized by a combination of spectroscopic, thermal analysis and electrochemical techniques.

Efficient synthesis of ω-mercaptoalkyl 1,2-trans-glycosides from sugar peracetates

Lewis acid-promoted reactions of peracetylated sugars (glucose, galactose, maltose, lactose) with ω-bromo-1-alkanols (C8, C12) were investigated. ZnCl2 was found to promote the 1,2-trans-glycosylation of the alcohols in toluene at about 60 °C in a stereocontrolled manner with better yields than commonly employed promoters such as SnCl4. The ω-bromoalkyl acetylated glycosides were readily converted to ω-mercaptoalkyl glycosides, which are useful for the preparation of glycoclusters.

Palladium catalyzed cross-coupling reaction of functional organozinc reagents with (2E,4E)- and (2E,4Z)-5-bromopenta-2,4-dienals: Easy access to functional conjugated dienic aldehydes

Functional zinc reagents can be applied to palladium catalyzed cross-coupling reaction with (2E,4E)- and (2E,4Z)-5-bromopenta-2,4-dienal. The corresponding functional dienic aldehydes were obtained in goods yields. From the (2E,4E) isomer, the (2E,4E) dienals were isolated as single isomer according to a total stereoselective reaction. But, from the (2E,4Z) isomer the coupling reaction has lead to a mixture of (2E,4E) and (2E,4Z) isomers. A mechanism for the loss of stereoselectivity in the last case is proposed.