- Rapid-acting insulin composition comprising a substituted citrate
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A composition, in the form of an aqueous solution, including an insulin in hexameric form and at least one substituted citrate of formula I: in which: R1, R2, R3, identical or different, represent OH or AA, at least one of
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Paragraph 0317; 0318; 0319; 0320; 0321
(2017/06/12)
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- Synthesis of citrate-ciprofloxacin conjugates
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Two regioisomeric citrate-functionalized ciprofloxacin conjugates have been synthesized and their antimicrobial activities against a panel of clinically-relevant bacteria have been determined. Cellular uptake mechanisms were investigated using wild-type and ompF deletion strains of Escherichia coli K-12.
- Md-Saleh, Siti R,Chilvers, Emily C.,Kerr, Kevin G.,Milner, Stephen J.,Snelling, Anna M.,Weber, Jan P.,Thomas, Gavin H.,Duhme-Klair, Anne-Kathrin,Routledge, Anne
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scheme or table
p. 1496 - 1498
(2009/11/30)
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- On the interactions of alkyl 2-hydroxycarboxylic acids with alkoxysilanes 2. Complexation and esterification of di- and tricarboxylic acids
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The selective esterifications of l-malic, l-tartaric and citric acids with tetramethoxysilane Si(OMe)4, in methanol (MeOH) have been demonstrated for the first time. The interactions between these acids and Si(OMe)4, and also between
- Ansell, Richard J.,Meegan, Jonathan E.,Barrett, Simon A.,Warrinner, Stuart L.
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scheme or table
p. 1460 - 1470
(2009/06/05)
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- Synthesis and biological evaluation of new citrate-based siderophores as potential probes for the mechanism of iron uptake in mycobacteria
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Several iron chelators containing α,β-unsaturated hydroxamic acid motifs appended to a citric acid platform were synthesized. Mycobacterium paratuberculosis was then challenged to grow in the presence of a panel of siderophores (mycobactin J, deferrioxami
- Guo, Hongyan,Naser, Saleh A.,Ghobrial, George,Phanstiel IV, Otto
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p. 2056 - 2063
(2007/10/03)
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- Synthesis and characterisation of tin(II) and tin(IV) citrates
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A series of tin(II) citrates, SnM(C6H4O7) (M = Sn or Zn) and SnMM′(C6H4O7) (M = M′ = Na, K or NH4; M = NMe4, M′ = H) and related monotin(II) salts of 1,5-dimethyl and 1,5-di-n-butyl citrate have been synthesized and characterised by spectroscopic methods (IR, 1H, 13C, 119Sn NMR, 119Sn Moessbauer). The crystal structures of dimeric tin(II) 1,5-dimethyl citrate and an oxidation product, Sn(NMe4)2(C6H5O7) 2·3.5H2O, have also been determined.
- Deacon, Paul R.,Mahon, Mary F.,Molloy, Kieran C.,Waterfield, Phillip C.
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p. 3705 - 3712
(2007/10/03)
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- A FACILE PREPARATION OF ASYM-MONOMETHYL, SYM-MONOMETHYL AND ASYM-DIMETHYL CITRATE
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Asym-monomethyl citrate was prepared by hydrolysis of sym-dimethyl citrate.Sym-monomethyl and sym-dimethyl citrate were prepared by a selective hydrolysis of trimethyl citrate.
- Hirota, Kazuhiro,Kitagawa, Harukazu,Shimamura, Michiya,Ohmori, Shinji
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p. 191 - 194
(2007/10/02)
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