53798-96-2

Usage

Uses

Used in Pharmaceutical Industry:
sym.-Dimethylcitrat is used as an intermediate in the production of Mosapride Citric Amide, a prokinetic agent used to treat gastrointestinal disorders such as gastroesophageal reflux disease (GERD) and functional dyspepsia. It helps to improve gastric emptying and reduce symptoms associated with these conditions.
Used in Chemical Industry:
sym.-Dimethylcitrat is used as a protected citrate in the chemical industry. It serves as a building block for the synthesis of various compounds and can be used to protect the carboxylic acid functional group during chemical reactions, preventing unwanted side reactions and facilitating the formation of the desired product.

Upstream product

• 681-84-5 tetramethylorthosilicate 
• 77-92-9 citric acid 
• 17094-36-9 dimethyl acetylmalonate 
• 107806-89-3 C₂₄H₂₇NO₉ 
• 7664-93-9 sulfuric acid 
• 67-56-1 methanol 
• 77862-72-7 (5-oxo-[1,3]dioxolane-4,4-diyl)-bis-acetic acid dimethyl ester 
• 56345-96-1 dimethyl 3-cyano-3-hydroxy-1,5-pentanedioate 

Downstream Products

• 542-05-2 acetonedicarboxylic acid 
• 1587-20-8 trimethyl citrate 
• 114340-51-1 2-tert-butyl 1,3-dimethyl 2-hydroxypropane-1,2,3-tricarboxylate 
• 69281-09-0 β-citryl-L-glutamic acid 
• 101996-62-7 citric acid α,α'-dibenzyl ester 
• 114340-59-9 N-[4-(Acetyl-benzyloxy-amino)-butyl]-2-{[4-(acetyl-benzyloxy-amino)-butylcarbamoyl]-methyl}-2-hydroxy-succinamic acid tert-butyl ester 
• 114340-58-8 N-[3-(Acetyl-benzyloxy-amino)-propyl]-2-{[3-(acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinamic acid tert-butyl ester 
• 114340-57-7 N-(4-Benzyloxyamino-butyl)-2-[(4-benzyloxyamino-butylcarbamoyl)-methyl]-2-hydroxy-succinamic acid tert-butyl ester 
• 114340-56-6 N-(3-Benzyloxyamino-propyl)-2-[(3-benzyloxyamino-propylcarbamoyl)-methyl]-2-hydroxy-succinamic acid tert-butyl ester 
• 114340-54-4 2-tert-butyl citrate 1,3-di-N-benzyl-amide 
• 35418-52-1 schizokinen 
• 153492-20-7 2-{[5-(Acetyl-benzyloxy-amino)-pentylcarbamoyl]-methyl}-N-{5-[benzyloxy-(3-methoxycarbonyl-propionyl)-amino]-pentyl}-2-hydroxy-succinamic acid tert-butyl ester 

Relevant academic research and scientific papers

Rapid-acting insulin composition comprising a substituted citrate

A composition, in the form of an aqueous solution, including an insulin in hexameric form and at least one substituted citrate of formula I: in which: R1, R2, R3, identical or different, represent OH or AA, at least one of

On the interactions of alkyl 2-hydroxycarboxylic acids with alkoxysilanes 2. Complexation and esterification of di- and tricarboxylic acids

The selective esterifications of l-malic, l-tartaric and citric acids with tetramethoxysilane Si(OMe)4, in methanol (MeOH) have been demonstrated for the first time. The interactions between these acids and Si(OMe)4, and also between

Synthesis of citrate-ciprofloxacin conjugates

Two regioisomeric citrate-functionalized ciprofloxacin conjugates have been synthesized and their antimicrobial activities against a panel of clinically-relevant bacteria have been determined. Cellular uptake mechanisms were investigated using wild-type and ompF deletion strains of Escherichia coli K-12.

Synthesis and biological evaluation of new citrate-based siderophores as potential probes for the mechanism of iron uptake in mycobacteria

Several iron chelators containing α,β-unsaturated hydroxamic acid motifs appended to a citric acid platform were synthesized. Mycobacterium paratuberculosis was then challenged to grow in the presence of a panel of siderophores (mycobactin J, deferrioxami

Synthesis and characterisation of tin(II) and tin(IV) citrates

A series of tin(II) citrates, SnM(C6H4O7) (M = Sn or Zn) and SnMM′(C6H4O7) (M = M′ = Na, K or NH4; M = NMe4, M′ = H) and related monotin(II) salts of 1,5-dimethyl and 1,5-di-n-butyl citrate have been synthesized and characterised by spectroscopic methods (IR, 1H, 13C, 119Sn NMR, 119Sn Moessbauer). The crystal structures of dimeric tin(II) 1,5-dimethyl citrate and an oxidation product, Sn(NMe4)2(C6H5O7) 2·3.5H2O, have also been determined.

A FACILE PREPARATION OF ASYM-MONOMETHYL, SYM-MONOMETHYL AND ASYM-DIMETHYL CITRATE

Asym-monomethyl citrate was prepared by hydrolysis of sym-dimethyl citrate.Sym-monomethyl and sym-dimethyl citrate were prepared by a selective hydrolysis of trimethyl citrate.