54044-79-0

Basic information

• Product Name: 2-BROMO-5-METHYL-1,3,4-THIADIAZOLE
• Synonyms: 1,3,4-thiadiazole, 2-bromo-5-methyl-;2-BroMo-5-Methyl-1,3,4-thiadiazole 97%;2-Bromo-5-methyl-1,3,4-thiadiazole97%
• CAS NO: 54044-79-0
• Molecular Formula: C₃H₃BrN₂S
• Molecular Weight: 179.04
• Product Categories: Halides;Oxadiazoles & Thiadiazoles;Oxadiazoles & Thiadiazoles
• Mol File: 54044-79-0.mol

Chemical Properties

• Melting Point: 105-106℃
• Boiling Point: 242 °C at 760 mmHg
• Flash Point: 100.1 °C
• Appearance: /
• Density: 1.83 g/cm³
• Vapor Pressure: 0.0541mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -0.90±0.10(Predicted)
• CAS DataBase Reference: 2-BROMO-5-METHYL-1,3,4-THIADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-5-METHYL-1,3,4-THIADIAZOLE(54044-79-0)
• EPA Substance Registry System: 2-BROMO-5-METHYL-1,3,4-THIADIAZOLE(54044-79-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 54044-79-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-BROMO-5-METHYL-1,3,4-THIADIAZOLE is used as a building block for the synthesis of pharmaceuticals, playing a crucial role in the development of new drugs. Its unique structure and reactivity allow for the creation of a wide range of medicinal compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-BROMO-5-METHYL-1,3,4-THIADIAZOLE serves as a key component in the synthesis of various agrochemicals. Its incorporation into these compounds can enhance their effectiveness in pest control, crop protection, and other agricultural applications.
Used in Organic Chemistry Research and Development:
2-BROMO-5-METHYL-1,3,4-THIADIAZOLE is utilized in the research and development of new materials and compounds. Its versatile reactivity enables chemists to explore various chemical reactions and syntheses, leading to the discovery of innovative organic compounds with potential applications in various industries.

InChI:InChI=1/C3H3BrN2S/c1-2-5-6-3(4)7-2/h1H3

Upstream product

• 108-33-8 5-methyl-1,3,4-thiadiazol-2-amine 
• 12775-96-1 copper 

Downstream Products

• 99137-58-3 1-[(4-fluorophenyl)methyl]-N-[1-[2-[(5-methyl-1,3,4-thiadiazol-2-yl)amino]ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine 
• 1097626-55-5 2-((2R,6S)-2,6-dimethylmorpholino)-3,4-difluoro-5-((5-methyl-1,3,4-thiadiazol-2-yl)ethynyl)benzaldehyde 
• 1177267-66-1 (trans)-8-({[6-(2-fluorophenyl)-3-pyridazinyl]amino}methyl)-3-(5-methyl-1,3,4-thiadiazol-2-yl)-1-oxa-3-azaspiro[4.5]decan-2-one 
• 1310531-83-9 2-(5-methyl-1,3,4-thiadiazol-2-yl)benzaldehyde 
• 1329669-50-2 [1-(5-Methyl-[1,3,4]thiadiazol-2-yl)-piperidin-4-yl]-(4-phenyl-4,5,6,7-tetrahydro-benzothiazol-2-yl)-amine 
• 1333472-89-1 4-(5-methyl-1,3,4-thiadiazole-2-yl)benzaldehyde 
• 3085-76-5 diisopropylcyanamide 

Relevant articles and documents

SOLUBLE GUANYLATE CYCLASE ACTIVATORS

A compound of Formula I or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (" cGMP") and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula I or a pharmaceutically acceptable salt thereof.

Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings

A compound of the formula (I): STR1 or pharmaceutical acceptable salts thereof wherein X is NR1, S(O)g, or O; R1 is H, C1-6 alkyl optionally substituted with one or more OH, CN, or halo, or R1 is --(CH2)h -- aryl, --COR1--1, --COOR1-2, --CO--(CH2)h --COR1--1, C1-6 alkyl sulfonyl, --SO2 --(CH2)h --aryl, or --(CO)i --Het; R2 is H, C1-6 alkyl, --(CH2)h --aryl, or halo; R3 and R4 are the same or different and are H or halo; R5 is H, C1-12 alkyl optionally substituted with one or more halo, C3-12 cycloalkyl, C1-6 alkoxy. The compounds are useful antimicrobial agents.