541508-27-4 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
Ethanone, 1-(5-chloro-2-fluorophenyl)(9CI) is used as a chemical intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and potential biological activity contribute to the development of new drugs with specific therapeutic effects.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, Ethanone, 1-(5-chloro-2-fluorophenyl)(9CI) serves as a valuable building block for the design and synthesis of novel drug candidates. Its structural features can be exploited to modulate the pharmacokinetic and pharmacodynamic properties of new molecules, enhancing their efficacy and safety profiles.
It is important to handle Ethanone, 1-(5-chloro-2-fluorophenyl)(9CI) with care and follow safety guidelines when working with it, as its specific properties and potential hazards may vary. Further research and testing may be necessary to fully understand the potential uses and risks associated with Ethanone, 1-(5-chloro-2-fluorophenyl)- (9CI).
Check Digit Verification of cas no
The CAS Registry Mumber 541508-27-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,1,5,0 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 541508-27:
(8*5)+(7*4)+(6*1)+(5*5)+(4*0)+(3*8)+(2*2)+(1*7)=134
134 % 10 = 4
So 541508-27-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H6ClFO/c1-5(11)7-4-6(9)2-3-8(7)10/h2-4H,1H3
541508-27-4Relevant articles and documents
Pd-Catalysed direct C(sp2)-H fluorination of aromatic ketones: Concise access to anacetrapib
Wu, Qiuzi,Mao, Yang-Jie,Zhou, Kun,Wang, Shuang,Chen, Lei,Xu, Zhen-Yuan,Lou, Shao-Jie,Xu, Dan-Qian
supporting information, p. 4544 - 4547 (2021/05/17)
The Pd-cataylsed direct ortho-C(sp2)-H fluorination of aromatic ketones has been developed for the first time. The reaction features good regioselectivity and simple operations, constituting an alternative shortcut to access fluorinated ketones. A concise synthesis of anacetrapib has also been achieved by using late-stage C-H fluorination as a key step.
