54794-73-9

Basic information

• Product Name: N-Isobutyloctadecanamide
• Synonyms: N-Isobutyloctadecanamide;OctadecanaMide, N-(2-Methylpropyl)-
• CAS NO: 54794-73-9
• Molecular Formula: C22H45NO
• Molecular Weight: 339.6
• Mol File: 54794-73-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Isobutyloctadecanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Isobutyloctadecanamide(54794-73-9)
• EPA Substance Registry System: N-Isobutyloctadecanamide(54794-73-9)

Safety Data

• Hazardous Substances Data: 54794-73-9(Hazardous Substances Data)

Upstream product

• 78-81-9 isobutylamine 
• 112-76-5 Stearoyl chloride 
• 57-11-4 stearic acid 

Relevant articles and documents

USE OF ENDOCANNABINOID-LIKE COMPOUNDS FOR TREATING CNS DEGENERATIVE DISORDERS

no abstract published

Biosynthesis of the structurally unique polycyclopropanated polyketide-nucleoside hybrid jawsamycin (FR-900848)

The biosynthetic gene cluster of antifungal agent jawsamycin (FR-900848) has been identified by heterologous expression. A series of gene inactivations and in vitro and in vivo analysis of key enzymes in the biosynthetic pathway established their functions. A novel mechanism involving a radical S-adenosyl methionine (SAM) cyclopropanase collaborating with an iterative polyketide synthase is proposed for the construction of the unique polycyclopropanated backbone. Our reconstitution system sets the stage for studying the catalytic mechanism of this intriguing contiguous cyclopropanation. Jaws of life: The biosynthetic gene cluster of antifungal agent jawsamycin (FR-900848) has been identified by heterologous expression. A series of gene inactivations and in vitro and in vivo analysis of the key enzymes established their functions. A novel iterative polyketide synthase is proposed to collaborate with a trans-acting ketoreductase and a radical SAM cyclopropanase in constructing the unique polycyclopropanated backbone.

Mass spectral characterization of fatty acid amides from alfalfa trichomes and their deterrence against the potato leafhopper

A homologous series of N-(3-methylbutyl)amides of normal saturated C 14, C15, C16, C17 and C18 fatty acids were identified as major components of glandular trichome extracts from Medicago sativa G98A, an alfalfa genotype resistant to the potato leafhopper, Empoasca fabae. A second homologous series of N-(2-methylpropyl) amides of C14 through C18 normal fatty acids were minor components. Saturated free fatty acids C12, C13, C 14, C15, C16, C17 and C18 were present in trace amounts, as was the N-(3-methylbutyl)amide of linoleic acid (C18:2). N-(3-methylbutyl)amides and N-(2-methylpropyl)amides of C14 through C18 fatty acids, along with the N-(3-methylbutyl)amide of linoleic acid, were synthesized and bioassayed for leafhopper deterrence by applying the compounds to the surface of a sachet containing an artificial diet. Leafhoppers were then offered a two-way choice between diet surfaces treated with the synthetic amides or an untreated control. N-(3-methylbutyl)amides and N-(2-methylpropyl)amides of C14 through C18 fatty acids did not deter leafhopper settling in a dose-dependent fashion. In contrast, when tested singly, N-(3-methylbutyl)amide of linoleic acid exhibited dose-dependent deterrence against leafhopper settling. Fatty acid amides localized in alfalfa glandular trichomes likely contribute to leafhopper resistance.