55204-93-8

Basic information

• Product Name: 2-CHLOROBENZYL ISOCYANATE
• Synonyms: TIMTEC-BB SBB006645;2-CHLOROBENZYL ISOCYANATE;2-CHLOROBENZYL ISOCYANATE 98%;2-Chlorobenzyl isocyanate,98%
• CAS NO: 55204-93-8
• Molecular Formula: C₈H₆ClNO
• Molecular Weight: 167.59
• Product Categories: Isocyanates;Nitrogen Compounds;Organic Building Blocks
• Mol File: 55204-93-8.mol

Chemical Properties

• Boiling Point: 238 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.149 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0493mmHg at 25°C
• Refractive Index: n20/D 1.547(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-CHLOROBENZYL ISOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROBENZYL ISOCYANATE(55204-93-8)
• EPA Substance Registry System: 2-CHLOROBENZYL ISOCYANATE(55204-93-8)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: UN 2206 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 55204-93-8(Hazardous Substances Data)

Usage

Chemical Properties

clear colourless to slightly yellow liquid

InChI:InChI=1/C8H6ClNO/c9-8-4-2-1-3-7(8)5-10-6-11/h1-4H,5H2

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 89-97-4 2-CHLOROBENZYLAMINE 
• 81777-89-1 clomazone 

Downstream Products

• 91467-02-6 C₁₀H₆Cl₃NO₃ 
• 1005738-51-1 3-(2-chlorobenzyl)-1-methyl-1-(2-(6-methyl-4-oxo-3,4-dihydroquinazolin-2-ylamino)ethyl)urea 
• 91467-14-0 5,5-Dichloro-3-(2-chloro-benzyl)-oxazolidine-2,4-dione 
• 735331-15-4 N-(2-chlorobenzyl)-N'-(1-methyl-1H-indazol-4-yl)urea 
• 898799-57-0 C₂₃H₂₅ClFN₅O₂ 
• 442683-03-6 2-Amino-N-(2-chlorobenzyl)-6-(2-furyl)-9H-purine-9-carboxamide 
• 1132825-05-8 4-[3-(4-morpholin-4-yl-phenylcarbamoyl)-phenyl]-piperazine-1-carboxylic acid 2-chloro-benzylamide 
• 917889-35-1 3-(2-chloro-benzyl)-2,4-dioxo-1,2,3,4-tetrahydro-quinazoline-7-carboxylic acid methyl ester 

Relevant articles and documents

Design and Synthesis of 4-Alkylidene-β-lactams: Benzyl- and Phenethyl-carbamates as Key Fragments to Switch on Antibacterial Activity

The emergence of multidrug-resistant bacterial strains is particularly important in chronic pathologies such as cystic fibrosis (CF), in which persistent colonization and selection of resistant strains is favored by the frequent and repeated use of antibacterial agents. Staphylococcus aureus is a common pathogen in CF patients that has an associated increased multidrug resistance. In previous studies we demonstrated that the presence of a 4-alkylidene side chain directly linked to a β-lactam appeared to strengthen the potency against S. aureus, especially against methicillin-resistant S. aureus (MRSA) strains. In the present study, 21 new 4-alkylidene-β-lactams were synthesized and evaluated for antibacterial activity. We designed the new compounds to have aryl, benzyl, or phenethyl-carbamate groups on the C3 hydroxyethyl side chain. We found a correlation between biological activity and the nitrogen substituent of the carbamate group, and two phenethyl-carbamate β-lactams were shown to be valuable antibacterial agents against selected linezolid-resistant strains, with a minimum inhibitory concentrations of 2–4 mg L?1.

Photoinduced degradation of the herbicide clomazone model reactions for natural and technical systems

The photodegradation of the herbicide clomazone in the presence of S 2O82- or of humic substances of different origin was investigated. A value of (9.4 ± 0.4) × 108 m-1 s-1 was measured for

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