81777-89-1 Usage
Description
The molecular target site of clomazone has recently
been determined. With clomazone, carotenoid synthesis
is inhibited, but no intermediates in the carotenoidcommitted
portion of the pathway accumulate (5,6).
Synthesis of the derivatives of GGPP (gibberellic acid,
phytol, carotenoids) is inhibited by clomazone (5–8).
However, the synthesis of certain sesquiterpenoids and
triterpenoids is not inhibited (9). Until recently, there was
no credible report of the effect of clomazone on any enzyme
of the terpenoid pathway (10–12). This was due to the
fact that clomazone is a proherbicide and that the proper
enzyme had not been tested.
Chemical Properties
Depending purity, it may be clear and colorless to pale yellow or brownish liquid. Commercially available as emulsifiable concentrates that can be dissolved in water
Uses
Herbicide.
Definition
ChEBI: A oxazolidinone that is 1,2-oxazolidin-3-one substituted by a 2-chlorobenzyl group at position 2 and two methyl groups at position 4.
Hazard
Moderately toxic by ingestion, inhalation,
and skin contact. A reproductive hazard.
Agricultural Uses
Herbicide: Clomazone is a broad-spectrum herbicide used on
rice, peas, pumpkins, soybeans, sweet potatoes, winter
squash, cotton, tobacco and fallow wheat fields to control
annual grasses and broadleaf weeds.
Trade name
CERANO?; COLZOR TRIO?;
COMMAND?; COMMENCE?, DIBEL?; FMC? 57020;
GAMBIT?; MAGISTER?; MERIT?; STRATEGY?
Potential Exposure
Clomazone is a oxazolidione broadspectrum herbicide used on rice, peas, pumpkins, soybeans, sweet potatoes, winter squash, cotton, tobacco, and fallow wheat fields to control annual grasses and broadleaf weeds.
Metabolic pathway
By the preparative incubation of clomazone with
microorganisms that have the ability to metabolize
clomazone, the metabolites are identified via major
biotransformation reactions which involve
hydroxylation at the 5-methylene carbon and one of
the 3-methyl groups of the isoxazolidone ring and at
the 3 0 -position of the phenyl ring. Minor metabolic
routes include dihydroxylation on the phenyl ring,
cleavage of the isoxazolinone ring, or complete
removal of the isoxazolinone ring to form
2-chlorobenzyl alcohol. Under aerobic conditions of
soils, degradation of clomazone proceeds primarily by
CO2 evolution and the formation of bound soil
residues. In flooded soils, clomazone is found rapidly
to degrade via the formation of the reductive product N-[(2-chlorophenyl)methyl]-3-hydroxy-2,2-
dimethylpropionamide. In tolerant soybean cell
suspension cultures, the only metabolite identified is
b-glycosyl-2-chlorobenzyl alcohol.
Shipping
UN2902 Pesticide, liquid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Waste Disposal
Do not discharge into drains or sewers. Dispose of waste material as hazardous waste using a licensed disposal contractor to an approved landfill. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.
Check Digit Verification of cas no
The CAS Registry Mumber 81777-89-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,7,7 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 81777-89:
(7*8)+(6*1)+(5*7)+(4*7)+(3*7)+(2*8)+(1*9)=171
171 % 10 = 1
So 81777-89-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3
