55499-44-0

Basic information

• Product Name: Boronic acid,B-(2,4-dimethylphenyl)-
• Synonyms: M-XYLENE-4-BORONIC ACID;AKOS BRN-0225;2,4-DIMETHYLPHENYLBORONIC ACID;2,4-DIMETHYLBENZENEBORONIC ACID;2,4-Dimethylphenylboronic;2,4-Dimethylphenylboronic Acid (contains varying amounts of Anhydride);2,4-Dimethylphenylboronic acid ,98%;4-Borono-m-xylene
• CAS NO: 55499-44-0
• Molecular Formula: C₈H₁₁BO₂
• Molecular Weight: 149.98
• Product Categories: Triazoles;B (Classes of Boron Compounds);Boronic acid;Organoborons;blocks;BoronicAcids;Boronic acids;Aryl
• Mol File: 55499-44-0.mol

Chemical Properties

• Melting Point: 204-208°C
• Boiling Point: 292.4 °C at 760 mmHg
• Flash Point: 130.7 °C
• Appearance: /
• Density: 1.07 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 8.92±0.58(Predicted)
• Water Solubility: Slightly soluble in water
• CAS DataBase Reference: Boronic acid,B-(2,4-dimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Boronic acid,B-(2,4-dimethylphenyl)-(55499-44-0)
• EPA Substance Registry System: Boronic acid,B-(2,4-dimethylphenyl)-(55499-44-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39-36/37-37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 55499-44-0(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

suzuki reaction

Upstream product

• 7732-18-5 water 
• 5419-55-6 Triisopropyl borate 
• 583-70-0 1-bromo-2,4-dimethylbenzene 
• 13675-18-8 tetrahydroxydiboron 

Downstream Products

• 950661-88-8 2-chloro-4-(2,4-dimethyl-phenyl)-7-(2-trimethylsilanyl-ethoxymethyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 
• 916174-19-1 4-(2,4-dimethyl-phenyl)-1H-pyrrolo[2,3-b]pyridine 
• 868371-72-6 3-(2,4-dimethylphenyl)-1-methyl-5-nitropyridin-2(1H)-one 
• 868372-09-2 5-(2,4-dimethylphenyl)-3-methyl-2-(methylthio)pyrimidin-4(3H)-one 
• 868374-54-3 5-(2,4-dimethylphenyl)-4-oxo-1-(1-propylbutyl)-1,4-dihydroquinoline-3-carbonitrile 
• 847560-54-7 2-amino-4-chloro-6-(2,4-dimethyl-phenyl)-pyrimidine-5-carbaldehyde 
• 446273-60-5 6-chloro-4-(2,4-dimethylphenyl)-3-pyridazineamine 
• 319474-10-7 3-Amino-4,6-dimethylphenyl boronic acid 
• 319474-09-4 2,4-dimethyl-5-nitro-phenyl boronic acid 
• 909186-40-9 6-chloro-1-(2.4-dimethylphenyl)phthalazine 
• 76708-79-7 2,4,4'-trimethylbiphenyl 

Relevant articles and documents

Bedford-type palladacycle-catalyzed miyaura borylation of aryl halides with tetrahydroxydiboron in water

A mild aqueous protocol for palladium catalyzed Miyaura borylation of aryl iodides, aryl bromides and aryl chlorides with tetrahydroxydiboron (BBA) as a borylating agent is developed. The developed methodology requires low catalyst loading of Bedford-type palladacycle catalyst (0.05 mol %) and works best under mild reaction conditions at 40 °C in short time of 6 h in water. In addition, our studies show that for Miyaura borylation using BBA in aqueous condition, maintaining a neutral reaction pH is very important for reproducibility and higher yields of corresponding borylated products. Moreover, our protocol is applicable for a broad range of aryl halides, corresponding borylated products are obtained in excellent yields up to 93% with 29 examples demonstrating its broad utility and functional group tolerance.

POLYMERIZABLE COMPOUND AND OPTICAL ANISOTROPIC BODY

PROBLEM TO BE SOLVED: To provide a polymerizable compound that has a high refractive index anisotropy, prevents the occurrence of crystal deposition or the like when added to a polymerizable liquid crystal composition and has high storage stability, also