583-70-0 Usage
Description
2,4-Dimethylbromobenzene, also known as 1-Bromo-2,4-dimethylbenzene, is an organic compound with the molecular formula C8H9Br. It is a clear, colorless to light yellow liquid that is used as a chemical intermediate in the synthesis of various organic compounds. It possesses unique chemical properties that make it a versatile building block in organic chemistry.
Uses
Used in Chemical Synthesis:
2,4-Dimethylbromobenzene is used as a chemical intermediate for the synthesis of various organic compounds. Its bromine atom can be replaced by other functional groups, making it a valuable starting material for the production of a wide range of chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,4-Dimethylbromobenzene is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
2,4-Dimethylbromobenzene is also utilized in the agrochemical industry for the synthesis of pesticides and other agrochemical products. Its chemical properties make it suitable for the development of compounds that can help protect crops from pests and diseases.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 2,4-Dimethylbromobenzene is used as a starting material for the synthesis of various dyes and pigments. Its chemical structure can be modified to produce a range of colors and properties, making it a valuable component in the production of dyes and pigments for various applications.
Used in Gold-Catalyzed Coupling Reactions:
2,4-Dimethylbromobenzene is used as a reactant in gold-catalyzed coupling reactions, such as the coupling of pyrazine with 1-bromo-2,4-dimethylbenzene. This reaction is an important step in the synthesis of complex organic molecules, which can be used in various applications, including pharmaceuticals, agrochemicals, and materials science.
Used in Synthesis of Aromatic Nitriles:
2,4-Dimethylbromobenzene is used in the synthesis of aromatic nitriles through a series of reactions involving magnesium (Mg), dimethylformamide (DMF), iodine (I2), and aqueous ammonia (aq.NH3). Aromatic nitriles are important intermediates in the production of various chemicals, including pharmaceuticals, agrochemicals, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 583-70-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,8 and 3 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 583-70:
(5*5)+(4*8)+(3*3)+(2*7)+(1*0)=80
80 % 10 = 0
So 583-70-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H9Br/c1-6-3-4-8(9)7(2)5-6/h3-5H,1-2H3
583-70-0Relevant articles and documents
Chemistry of ethanediyl S,S-acetals 6-an example of vicarious nucleophilic substitution of hydrogen in 1,4-benzodithians
Caputo, Romualdo,De Nisco, Mauro,Palumbo, Giovanni,Adamo, Carlo,Barone, Vincenzo
, p. 11383 - 11388 (1993)
1,4-Benzodithians, when treated with bromine in anhydrous chloroform, undergo very fast monobromination at the aromatic ring. By the use of quantum mechanical semiempirical calculations, the reaction is shown to proceed most likely via a vicarious nucleophilic substitution of hydrogen.
Molecular tweezers based on trivalent phosphine, preparation method of molecular tweezers, metal-molecular tweezers catalyst, and preparation method and application of metal-molecular tweezers catalyst
-
Paragraph 0038; 0059-0060, (2020/12/14)
The invention relates to the technical field of inorganic-metal organic crossing and relates to the technical field of molecular tweezers, in particular to molecular tweezers based on trivalent phosphine, a preparation method of the molecular tweezers, a metal-molecular tweezer catalyst, a preparation method of the metal-molecular tweezer catalyst and an application of the metal-molecular tweezercatalyst, the molecular tweezer based on trivalent phosphine is named as P-MV-PCN-521-R, and R is any one of benzoic acid, p-nitrobenzoic acid, formic acid, p-methylbenzoic acid and dichloroacetic acid. The molecular tweezers based on the trivalent phosphine have distance adjustability. The trivalent phosphine-based metal-molecular tweezer catalyst provided by the invention has a high crystallinesurface area and a high specific surface area. The trivalent phosphine-based metal-molecular tweezer catalyst has good chemical stability and thermal stability, and is a primary condition for applyingthe trivalent phosphine-based metal-molecular tweezer catalyst to the actual field. The trivalent phosphine-based metal-molecular tweezer catalyst with adjustable distance provided by the invention has good selectivity for bromination of aromatic compounds.
Regioselective Halogenation of Arenes and Heterocycles in Hexafluoroisopropanol
Tang, Ren-Jin,Milcent, Thierry,Crousse, Benoit
, p. 930 - 938 (2018/01/28)
Regioselective halogenation of arenes and heterocycles with N-halosuccinimides in fluorinated alcohols is disclosed. Under mild condition reactions, a wide diversity of halogenated arenes are obtained in good yields with high regioselectivity. Additionally, the versatility of the method is demonstrated by the development of one-pot sequential halogenation and halogenation-Suzuki cross-coupling reactions.