55750-49-7Relevant articles and documents
Inactivation method
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Page/Page column 16, (2016/05/19)
The present invention relates to the field of thermostable enzymes, methods for their inactivation, and related uses, kits and reagents. In particular, the invention relates to a method for reversible inactivation of thermophilic enzymes by chemical modification under aqueous or non-aqueous conditions.
Indium-Catalyzed Amide Allylation of N-Carbonyl Imides: Formation of Azaspiro-γ-lactones via Ring Opening-Reclosure
Sengoku, Tetsuya,Murata, Yusuke,Aso, Yuwa,Kawakami, Ai,Inuzuka, Toshiyasu,Sakamoto, Masami,Takahashi, Masaki,Yoda, Hidemi
supporting information, p. 5846 - 5849 (2015/12/11)
A novel and facile synthesis of azaspiro-γ-lactones with a methylene-lactam framework from N-carbonyl imides is described. Mechanistic investigations provide evidence for a two-step reaction process involving ZnCl2-promoted addition of β-amido allylindium species followed by an unexpectedly molecular-sieves-mediated ring opening-reclosure concomitantly with the loss of an N-carbonyl unit.
Dendrimer-like polymeric DNAs as chemiluminescence probes for amplified detection of telomere DNA on a solid-phase membrane
El-Mahdy, Ahmed F. M.,Shibata, Takayuki,Kabashima, Tsutomu,Kai, Masaaki
supporting information, p. 859 - 861 (2014/01/06)
For the first time, an amplified chemiluminescence (CL) detection of the telomere DNA spotted on a nylon membrane is described here, based on the direct hybridization with the CL probe of dendrimer-like polymeric DNAs possessing a large number of guanine moieties. This probe was synthesized by sense and antisense hybridization between Y-shaped DNAs and then could hybridize with the target DNA. The Royal Society of Chemistry.
Novel compositions magnetic particles covered with gem-bisphosphonate derivatives
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, (2010/12/29)
The invention relates to a composition comprising acid magnetic particles (p) based on an iron compound, the acid magnetic particles (p) being complexed by one or more gem-bisphosphonate compounds, of formula I: [in-line-formulae]X-L-CH(PO3H2)2 ??(I)[/in-line-formulae]in which: L represents an organic group connecting the X group to the gem-bisphosphonate group —CH(PO3H2)2;X represents a chemical group capable of reacting with a biovector; all or some of the X groups of the particles optionally being coupled to a biovector. The invention relates also to a process for the preparation of the compositions and their use, in particular as contrast products for Magnetic Resonance Imaging (MRI).