139112-38-2

Basic information

• Product Name: Tris-(2-MaleiMidoethyl)aMine(Trifunctional)(TMEA)
• Synonyms: Tris-(2-MaleiMidoethyl)aMine(Trifunctional)(TMEA)
• CAS NO: 139112-38-2
• Molecular Formula: C₁₈H₁₈N₄O₆
• Molecular Weight: 386.36
• Mol File: 139112-38-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 618.3±50.0 °C(Predicted)
• Appearance: /
• Density: 1.479±0.06 g/cm3(Predicted)
• PKA: 6.37±0.50(Predicted)
• CAS DataBase Reference: Tris-(2-MaleiMidoethyl)aMine(Trifunctional)(TMEA)(CAS DataBase Reference)
• NIST Chemistry Reference: Tris-(2-MaleiMidoethyl)aMine(Trifunctional)(TMEA)(139112-38-2)
• EPA Substance Registry System: Tris-(2-MaleiMidoethyl)aMine(Trifunctional)(TMEA)(139112-38-2)

Safety Data

• Hazardous Substances Data: 139112-38-2(Hazardous Substances Data)

Usage

General Description

Tris-(2-MaleiMidoethyl)aMine (TMEA) is a trifunctional chemical compound that contains three maleimide functional groups. It is commonly used as a crosslinking agent in the production of polymers and resins, as well as in the synthesis of nanoparticles and other materials. TMEA is known for its high reactivity and ability to form strong covalent bonds, making it a valuable tool in various fields of chemistry and materials science. Its trifunctional nature allows for the creation of highly crosslinked and stable structures, while its maleimide groups provide specific reactivity towards thiol-containing molecules, making it useful for bioconjugation and biomaterials applications. TMEA is also used as a building block in the production of complex organic compounds, and its versatile reactivity makes it a valuable component in the synthesis of a wide range of functional materials.

Upstream product

• 108-31-6 maleic anhydride 
• 4097-89-6 2,2',2''-triaminotriethylamine 
• 55750-49-7 N-ethoxycarbonylmaleinimide 
• 55750-48-6 N-methoxycarbonylmaleimide 

Relevant articles and documents

Dendrimer-like polymeric DNAs as chemiluminescence probes for amplified detection of telomere DNA on a solid-phase membrane

For the first time, an amplified chemiluminescence (CL) detection of the telomere DNA spotted on a nylon membrane is described here, based on the direct hybridization with the CL probe of dendrimer-like polymeric DNAs possessing a large number of guanine moieties. This probe was synthesized by sense and antisense hybridization between Y-shaped DNAs and then could hybridize with the target DNA. The Royal Society of Chemistry.

Star polymer synthesis: Via λ-orthogonal photochemistry

We introduce a light induced sequence enabling λ-orthogonal star polymer formation via an arms-first approach, based on an α,ω-functional polymer carrying tetrazole and o-methyl benzaldehyde moieties, which upon irradiation can readily undergo cycloaddition with a trifunctional maleimide core. Depending on the wavelength, the telechelic strand can be attached to the core at either photo-reactive end.

Reversible polymer composition

A composition includes a reversible polymer material, which can reversibly transition between a liquid state and a solid state by reversible cycloaddition reactions, wherein upon cooling, the reversible polymer material transitions from a liquid state to a solid state by reversible cycloaddition reactions within a time period of less than about 10 seconds.