5577-48-0

Basic information

• Product Name: 2-HEXANONE OXIME
• Synonyms: 2-HEXANONE OXIME;Methyl n-butyl ketoxime;hexan-2-one oxime;2-HEXANONE OXIME 97%;2-Hexanone oxime, syn+anti, 97%;Methyl butyl ketoxime;Einecs 226-953-4;Methyl N-butyl ketone oxime
• CAS NO: 5577-48-0
• Molecular Formula: C₆H₁₃NO
• Molecular Weight: 115.17
• EINECS: 226-953-4
• Mol File: 5577-48-0.mol

Chemical Properties

• Boiling Point: 187.5 °C at 760 mmHg
• Flash Point: 94 °C
• Appearance: /
• Density: 0.89 g/cm³
• Vapor Pressure: 0.282mmHg at 25°C
• Refractive Index: 1.435
• CAS DataBase Reference: 2-HEXANONE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HEXANONE OXIME(5577-48-0)
• EPA Substance Registry System: 2-HEXANONE OXIME(5577-48-0)

Safety Data

• Safety Statements: S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 5577-48-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2-HEXANONE OXIME is used as a chemical intermediate for the synthesis of various chemicals and pharmaceuticals, contributing to the development of new compounds and medicines.
Used in Pesticide and Herbicide Production:
In the agricultural industry, 2-HEXANONE OXIME is utilized as a chemical intermediate in the production of pesticides and herbicides, helping to control pests and weeds for better crop yields.
Used in Coatings, Adhesives, and Sealants:
2-HEXANONE OXIME is used as a component in the formulation of coatings, adhesives, and sealants due to its properties that enhance the performance and durability of these products in various applications.
Used in Pharmaceutical Industry:
2-HEXANONE OXIME is used as a chemical intermediate in the pharmaceutical industry for the synthesis of various drugs, aiding in the development of new medications to treat a range of health conditions.

InChI:InChI=1/C6H13NO/c1-3-4-5-6(2)7-8/h8H,3-5H2,1-2H3/b7-6-

Upstream product

• 110-54-3 hexane 
• 591-78-6 n-hexan-2-one 

Downstream Products

• 591-78-6 n-hexan-2-one 
• 1128264-41-4 4-n-butyl-2-phenyl-1H-pyrrole 
• 70492-67-0 (S)-hexan-2-amine 
• 5329-79-3 (R)‐2‐aminohexane 
• 19692-48-9 Butyl-methyl-ketonoxim-pikrylether 

Relevant articles and documents

Arylboronic Acid-Catalyzed C-Allylation of Unprotected Oximes: Total Synthesis of N-Me-Euphococcine

O-Unprotected keto-and aldoximes are readily C-allylated with allyl diisopropyl boronate in the presence of arylboronic acid catalysts to yield highly substituted N-α-secondary and tertiary homoallylic hydroxylamines. The method was used in the total synthesis of the trace alkaloid N-Me-Euphococcine.

Iminyl Radical-Triggered Intermolecular Distal C(sp3)-H Heteroarylation via 1,5-Hydrogen-Atom Transfer (HAT) Cascade

An efficient iron-catalyzed intermolecular remote C(sp3)-H heteroarylation of alkyl ketones has been developed via an iminyl radical-triggered 1,5-hydrogen-atom transfer (HAT) cascade. This protocol was amenable to a wide variety of alkyl ketones and heteroaryls, thus providing a straightforward method for the late-stage functionalization of alkylketones and heteroaryls.

Iminyl Radical-Mediated Controlled Hydroxyalkylation of Remote C(sp3)-H Bond via Tandem 1,5-HAT and Difunctionalization of Aryl Alkenes

A visible-light mediated γ-hydroxyalkylation of ketones via C(sp3)-H functionalization has been developed under redox neutral conditions. This protocol relies on the iminyl radical-triggered 1,5-HAT followed by oxyalkylation of alkenes, wherein C?C and C?O bonds were constructed in one step. This three-component reaction features mild conditions, wide substrate scope and excellent functional group tolerance, thus providing a facile and highly efficient access to complex valuable ketones. (Figure presented.).