56517-33-0

Basic information

• Product Name: AKOS B005169
• Synonyms: CHEMBRDG-BB 6446149;AKOS B005169;2-BROMO-4-ISOPROPOXY-5-METHOXYBENZALDEHYDE;ART-CHEM-BB B005169;VITAS-BB TBB008069;2-bromo-4-isopropoxy-5-methoxybenzaldehyde(SALTDATA: FREE);2-bromo-5-methoxy-4-propan-2-yloxybenzaldehyde
• CAS NO: 56517-33-0
• Molecular Formula: C₁₁H₁₃BrO₃
• Molecular Weight: 273.12
• Mol File: 56517-33-0.mol

Chemical Properties

• Boiling Point: 337°C at 760 mmHg
• Flash Point: 157.6°C
• Appearance: /
• Density: 1.374g/cm³
• Vapor Pressure: 0.000108mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: AKOS B005169(CAS DataBase Reference)
• NIST Chemistry Reference: AKOS B005169(56517-33-0)
• EPA Substance Registry System: AKOS B005169(56517-33-0)

Safety Data

• Hazardous Substances Data: 56517-33-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H13BrO3/c1-7(2)15-11-5-9(12)8(6-13)4-10(11)14-3/h4-7H,1-3H3

Upstream product

• 2538-98-9 4-isopropyloxy-3-methoxybenzaldehyde 

Downstream Products

• 94283-75-7 2-bromo-4-isopropoxy-5-methoxybenzylalcohol 
• 56517-10-3 [1-(2-Bromo-4-isopropoxy-5-methoxy-phenyl)-meth-(E)-ylidene]-(6,7-dimethoxy-naphthalen-1-yl)-amine 
• 94283-77-9 2-bromo-4-isopropoxy-5-methoxybenzyl chloride 
• 94283-79-1 2-bromo-4-isopropoxy-5-methoxybenzylcyanide 
• 94283-83-7 2-bromo-4-isopropoxy-5-methoxyphenylacetic acid 
• 94283-84-8 N-(3-hydroxyphenethyl)-2-(4-isopropoxy-3-methoxyphenyl)acetamide 
• 94283-86-0 N-(3-hydroxyphenethyl)-2-(2-bromo-4-isopropoxy-5-methoxyphenyl)acetamide 
• 94283-85-9 N-(3-tosyloxyphenethyl)-2-(2-bromo-4-isopropoxy-5-methoxyphenyl)acetamide 
• 1108621-53-9 4-isopropoxy-2-[2-(3-isopropoxy-4-methoxyphenyl)ethynyl]-5-methoxybenzaldehyde 
• 1108621-60-8 2-(2-(3-isopropoxy-4-methoxystyryl)-4-isopropoxy-5-methoxyphenyl)ethoxime 
• 1108621-62-0 1-(3-isopropoxy-4-methoxybenzyl)-1,2,3,4-tetrahydro-7-isopropoxy-6-methoxyisoquinoline-N-hydroxide 
• 1108621-35-7 (Z)-2-[-2-(3-isopropoxy-4-methoxystyryl)-4-isopropoxy-5-methoxyphenyl]-N-hydroxyethanamine 
• 1108621-37-9 (Z)-2-[2-(3-isopropoxy-4-methoxystyryl)-4-isopropoxy-5-methoxyphenyl]-N-hydroxy-2-methylprop-2-en-1-amine 
• 13168-51-9 N-benzoyl-norreticuline 

Relevant articles and documents

New synthetic procedure for 2-aryl-1,4-naphthoquinone-1-oxime methyl ethers with potent antitumor activity

1,4-Naphthoquinone 1-oxime methyl ethers carrying an ester-substituted aryl pendant at 2-position were concisely prepared as seed compounds with structural flexibility for structure-activity relationship studies on antitumor activity. The key synthetic in

Studies on difficult intramolecular hydroaminations in the context of four syntheses of alkaloid natural products

Examples of intramolecular alkene hydroaminations forming six-membered ring systems are rare, especially for systems in which the double bond is disubstituted. Such cyclizations have important synthetic relevance. Herein we report a systematic study of these cyclizations using recently developed Cope-type hydroamination methodologies. Difficult intramolecular alkene hydroaminations were used as key steps in syntheses of 2-epi-pumiliotoxin C, coniine, N-norreticuline and desbromoarborescidine A. This effort required the development of optimized hydroamination conditions to improve the efficiency of the cyclizations. Collectively, our results show that Cope-type cyclizations can be achieved on a variety of challenging substrates and proceed under similar conditions for both N-H and N-substituted hydroxylamines.

Synthesis and biological activity of some antitumor benzophenanthridinium salts

A facile synthesis of benzophenanthridinium salts was developed and used for preparing a number of these compounds. The antitumor activities in mouse leukemia L1210 (LE) and P388 (PS) were determined as well as some selected antimicrobial activities. Alth