1108621-53-9

Basic information

• Product Name: 4-isopropoxy-2-[2-(3-isopropoxy-4-methoxyphenyl)ethynyl]-5-methoxybenzaldehyde
• Synonyms: 4-isopropoxy-2-[2-(3-isopropoxy-4-methoxyphenyl)ethynyl]-5-methoxybenzaldehyde
• CAS NO: 1108621-53-9
• Molecular Weight: 382.456
• Mol File: 1108621-53-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-isopropoxy-2-[2-(3-isopropoxy-4-methoxyphenyl)ethynyl]-5-methoxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-isopropoxy-2-[2-(3-isopropoxy-4-methoxyphenyl)ethynyl]-5-methoxybenzaldehyde(1108621-53-9)
• EPA Substance Registry System: 4-isopropoxy-2-[2-(3-isopropoxy-4-methoxyphenyl)ethynyl]-5-methoxybenzaldehyde(1108621-53-9)

Safety Data

• Hazardous Substances Data: 1108621-53-9(Hazardous Substances Data)

Upstream product

• 215715-43-8 β,β-dibromo-3-isopropoxy-4-methoxystyrene 
• 34123-66-5 O-isopropylisovanillin 
• 2538-98-9 4-isopropyloxy-3-methoxybenzaldehyde 
• 56517-33-0 4-isopropoxy-2-bromo-5-methoxybenzaldehyde 
• 439585-86-1 4-ethynyl-2-isopropoxy-1-methoxybenzene 

Downstream Products

• 1108621-54-0 1-isopropoxy-5-[2-(3-isopropoxy-4-methoxyphenyl)ethynyl]-2-methoxy-4-[(E)-2-nitrovinyl]benzene 
• 1108621-60-8 2-(2-(3-isopropoxy-4-methoxystyryl)-4-isopropoxy-5-methoxyphenyl)ethoxime 
• 1108621-62-0 1-(3-isopropoxy-4-methoxybenzyl)-1,2,3,4-tetrahydro-7-isopropoxy-6-methoxyisoquinoline-N-hydroxide 
• 1108621-35-7 (Z)-2-[-2-(3-isopropoxy-4-methoxystyryl)-4-isopropoxy-5-methoxyphenyl]-N-hydroxyethanamine 
• 1108621-37-9 (Z)-2-[2-(3-isopropoxy-4-methoxystyryl)-4-isopropoxy-5-methoxyphenyl]-N-hydroxy-2-methylprop-2-en-1-amine 
• 13168-51-9 N-benzoyl-norreticuline 
• 1108621-45-9 1-(3-isopropoxy-4-methoxybenzyl)-1,2,3,4-tetrahydro-7-isopropoxy-6-methoxyisoquinoline 

Relevant articles and documents

Studies on difficult intramolecular hydroaminations in the context of four syntheses of alkaloid natural products

Examples of intramolecular alkene hydroaminations forming six-membered ring systems are rare, especially for systems in which the double bond is disubstituted. Such cyclizations have important synthetic relevance. Herein we report a systematic study of these cyclizations using recently developed Cope-type hydroamination methodologies. Difficult intramolecular alkene hydroaminations were used as key steps in syntheses of 2-epi-pumiliotoxin C, coniine, N-norreticuline and desbromoarborescidine A. This effort required the development of optimized hydroamination conditions to improve the efficiency of the cyclizations. Collectively, our results show that Cope-type cyclizations can be achieved on a variety of challenging substrates and proceed under similar conditions for both N-H and N-substituted hydroxylamines.