56705-85-2

Basic information

• Product Name: 4-(2-Chlorophenoxy)benzamide
• Synonyms: 4-(2-Chlorophenoxy)benzamide;[4-(2-chlorophenoxy)phenyl]amine;4-(2-Chlorophenoxy)benzenamine;Albb-010109;4-(2-chlorophenoxy)aniline(SALTDATA: FREE);4-Amino-2'-chlorodiphenyl ether;2'-Chloro-4-aminobiphenyl ether;p-(o-Chlorophenoxy)aniline
• CAS NO: 56705-85-2
• Molecular Formula: C₁₂H₁₀ClNO
• Molecular Weight: 219.67
• Mol File: 56705-85-2.mol

Chemical Properties

• Melting Point: 81-83℃
• Boiling Point: 331.9 °C at 760 mmHg
• Flash Point: 154.5 °C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 0.000151mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-(2-Chlorophenoxy)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Chlorophenoxy)benzamide(56705-85-2)
• EPA Substance Registry System: 4-(2-Chlorophenoxy)benzamide(56705-85-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 56705-85-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-(2-Chlorophenoxy)benzamide is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, potentially contributing to the treatment of various medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 4-(2-Chlorophenoxy)benzamide serves as an intermediate in the production of pesticides and other crop protection agents. Its incorporation into these products can enhance their effectiveness in managing pests and diseases, thereby supporting agricultural productivity.
Used in Organic Chemistry Research:
4-(2-Chlorophenoxy)benzamide is utilized as a building block in organic chemistry, facilitating the creation of a wide range of chemical compounds. Its presence in various synthetic pathways makes it an essential tool for researchers and chemists working on the development of novel organic molecules for diverse applications.

InChI:InChI=1/C12H10ClNO/c13-11-3-1-2-4-12(11)15-10-7-5-9(14)6-8-10/h1-8H,14H2

Upstream product

• 56966-69-9 2-chloro-4-nitro-1-phenoxy-benzene 
• 64-17-5 ethanol 
• 2091-61-4 1-chloro-2-(4-nitrophenoxy)benzene 
• 7803-57-8 hydrazine hydrate 

Downstream Products

• 23813-35-6 N-[4-(2-Chloro-phenoxy)-phenyl]-N'-[1-nitro-eth-(Z)-ylidene]-hydrazine 
• 56884-83-4 3-[4-(2-chloro-phenoxy)-phenyl]-2-(4-nitro-phenyl)-thiazolidin-4-one 
• 56884-82-3 3-[4-(2-chloro-phenoxy)-phenyl]-2-phenyl-thiazolidin-4-one 
• 56884-84-5 3-[4-(2-chloro-phenoxy)-phenyl]-2-(4-methoxy-phenyl)-thiazolidin-4-one 
• 56885-02-0 3-[4-(2-chloro-phenoxy)-phenyl]-2-trichloromethyl-thiazolidin-4-one 
• 57181-41-6 2-Chloro-3-[4-(2-chloro-phenoxy)-phenyl]-propionic acid ethyl ester 
• 23748-00-7 1-[4-(2-Chloro-phenoxy)-phenyl]-3-(4-trifluoromethyl-phenyl)-urea 
• 57181-64-3 Sodium; 2-chloro-3-[4-(2-chloro-phenoxy)-phenyl]-propionate 
• 93869-66-0 4-<2-Chlor-phenoxy>-diphenylthioaether 
• 1082915-00-1 (S)-tert-butyl 1-(4-(2-chlorophenoxy)phenylamino)-1-oxopropan-2-ylcarbamate 
• 1366234-32-3 C₁₆H₁₃ClN₄O 
• 1613336-69-8 N-(4-(2-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodobenzamide 

Relevant articles and documents

Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors

The synthesis and biological evaluation of a series of aryl diamines as inhibitors of LTA4-h inhibitors are described. The optimization which led to the identification of the optimal para-substitution on the diphenyl ether moiety and diamine spacer is discussed. The resulting compounds such as 3l have excellent enzyme and cellular potency as well as desirable pharmacokinetic properties.

Derivatives of quinoline as inhibitors for MEK

1. A compound of formula (I) or a pharmaceutically acceptable salt thereof. wherein: n is 0-1; X and Y are independently selected from -NH-, -O-, -S-, or -NR8- where R8 is alkyl of 1-6 carbon atoms and X may additionally comprise a CH2 group; R7 is a group (CH2)mR9 where m is 0,or an integer of from 1-3 and R9 is a substituted aryl group, an optionally substituted cycloalkyl ring of up to 10 carbon atoms, or an optionally substituted heterocyclic ring or an N-oxide of any nitrogen containing ring; R6 is a divalent cycloalkyl of 3 to 7 carbon atoms, which may be optionally further substituted with one or more alkyl of 1 to 6 carbon atom groups; or is a divalent pyridinyl, pyimidinyl, or phenyl ring; wherein the pyridinyl, pyrimidinyl, or phenyl ring may be optionally further substituted with one or more specified groups; R1, R2, R3 and R4 are each independently selected from hydrogen or various specified organic groups. Compounds are useful as pharmaceuticals for the inhibition of MEK activity.