The Xanthene-9-spiro-4'-piperidine Nucleus as a Probe for Opiate Activity
A series of novel 1'-methylxanthene-9-sspiro-4'-piperidines has been prepared in the search for opiate analgesics with improved pharmacological properties.It has been found that intriduction of a hydroxyl group into the 4-position of the xanthenespiropipe
Galt, Ronald H. B.,Horbury, John,Matusiak, Zbigniew S.,Pearce, Robert J.,Shaw, John S.