B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of: In situ -formed enamines
A highly efficient B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of in situ-formed enamines in the presence of water and pinacolborane was developed. Regioselective β-deuteration of tertiary amines was achieved with high chemo- and regioselectivity. D2O was used as a readily available and cheap source of deuterium. Mechanistic studies indicated that B(C6F5)3 could activate water to promote the protonation and reduction of enamines. This journal is
Wu, Rongpei,Gao, Ke
supporting information
p. 4032 - 4036
(2021/05/19)
Aldehyde-Derived Enamines; A New One-Pot Synthesis from Substituted Acetic Acids
-
Knorr, Rudolf,Loew, Peter,Hassel, Petra
p. 785 - 786
(2007/10/02)
More Articles about upstream products of 58047-49-7