58231-00-8 Usage
Uses
Used in Pharmaceutical Industry:
3-Cyanothiophene-2-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Cyanothiophene-2-carboxylic acid serves as a building block for the creation of novel agrochemicals, such as pesticides and herbicides, that can improve crop protection and yield.
Used in Dye Industry:
3-Cyanothiophene-2-carboxylic acid is utilized in the production of dyes, where its chemical properties contribute to the development of new colorants with enhanced properties, such as improved colorfastness and stability.
Used in Organic Chemistry Research:
As a versatile organic compound, 3-Cyanothiophene-2-carboxylic acid is employed in organic chemistry research for the exploration of new synthetic pathways, reaction mechanisms, and the discovery of novel chemical transformations.
Used in Material Science:
3-Cyanothiophene-2-carboxylic acid has potential applications in the development of new materials, such as polymers and composites, that can exhibit unique properties, including improved electrical conductivity, thermal stability, and mechanical strength.
Used in Electronic Devices:
Due to its unique chemical properties, 3-Cyanothiophene-2-carboxylic acid may be employed in the development of electronic devices, such as organic light-emitting diodes (OLEDs), solar cells, and sensors, where its incorporation can enhance device performance and functionality.
Check Digit Verification of cas no
The CAS Registry Mumber 58231-00-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,2,3 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 58231-00:
(7*5)+(6*8)+(5*2)+(4*3)+(3*1)+(2*0)+(1*0)=108
108 % 10 = 8
So 58231-00-8 is a valid CAS Registry Number.
58231-00-8Relevant articles and documents
DNA binding ligands targeting drug-resistant bacteria: Structure, activity, and pharmacology
Kaizerman, Jacob A.,Gross, Matthew I.,Ge, Yigong,White, Sarah,Hu, Wenhao,Duan, Jian-Xin,Baird, Eldon E.,Johnson, Kirk W.,Tanaka, Richard D.,Moser, Heinz E.,Bürli, Roland W.
, p. 3914 - 3929 (2007/10/03)
We describe the lead optimization and structure-activity relationship of DNA minor-groove binding ligands, a novel class of antibacterial molecules. These compounds have been shown to target A/T-rich sites within the bacterial genome and, as a result, inhibit DNA replication and RNA transcription. The optimization was focused on N-terminal aromatic heterocycles and C-terminal amines and resulted in compounds with improved in vivo tolerability and excellent in vitro antibacterial potency (MIC ≥ 0.031 μg/mL) against a broad range of Gram-positive pathogens, including drug-resistant strains such as methicillin-resistant Stapylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP), and vancomycin-resistant Enterococcus faecalis (VRE). In a first proof-of-concept study, a selected compound (35) showed in vivo efficacy in a mouse peritonitis model against methicillin-sensitive S. aureus infection with an ED50 value of 30 mg/kg.
Phosphorylamides, their preparation and use
-
, (2008/06/13)
A phosphorylamide derivative represented by the general formula (I): STR1 wherein R represents an amino group that may be substituted, or a salt thereof, possesses potent antibacterial activity against Helicobacter bacterium, especially Helicobacter pylori, and is useful for prevention or treatment of digestive diseases caused by Helicobacter bacterium, solely or in combination with an antacid or an acid secretion inhibitor.
