58481-10-0

Basic information

• Product Name: 2-IODO-ISONICOTINIC ACID
• Synonyms: 2-IODO-ISONICOTINIC ACID;2-Iodopyridine-4-carboxylic acid;2-Iodopyridine-4-carboxylic ac;2-Iodo-4-pyridinecarboxylic acid
• CAS NO: 58481-10-0
• Molecular Formula: C₆H₄INO₂
• Molecular Weight: 249.01
• EINECS: -0
• Product Categories: pyridine
• Mol File: 58481-10-0.mol

Chemical Properties

• Melting Point: 210-220°C
• Boiling Point: 466.545 °C at 760 mmHg
• Flash Point: 235.958 °C
• Appearance: /
• Density: 2.124 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.677
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.02±0.10(Predicted)
• CAS DataBase Reference: 2-IODO-ISONICOTINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODO-ISONICOTINIC ACID(58481-10-0)
• EPA Substance Registry System: 2-IODO-ISONICOTINIC ACID(58481-10-0)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 58481-10-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2-IODO-ISONICOTINIC ACID is used as a reagent in various chemical reactions for its ability to participate in a range of chemical transformations. Its iodine atom can be a key factor in these reactions, facilitating the synthesis of new compounds or intermediates.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-IODO-ISONICOTINIC ACID is used as a starting material or intermediate in the synthesis of potential drug candidates. Its reactivity and structural features make it a valuable component in the development of new medications.
Used in Analytical Chemistry:
2-IODO-ISONICOTINIC ACID is used as an analytical reagent in various analytical techniques, such as spectroscopy or chromatography, to identify or quantify specific compounds. Its unique properties can aid in the detection and analysis of target substances in complex mixtures.
Used in Material Science:
In the field of material science, 2-IODO-ISONICOTINIC ACID is used as a component in the development of new materials with specific properties. Its reactivity can contribute to the formation of novel materials with potential applications in various industries.

InChI:InChI=1/C6H4INO2/c7-5-3-4(6(9)10)1-2-8-5/h1-3H,(H,9,10)

Upstream product

• 6313-54-8 2-chloroisonicotinic acid, 

Downstream Products

• 134579-47-8 methyl 2-iodoisonicotinate 
• 1322094-88-1 N-(2-{4-[5-(benzyloxy)pyridin-2-yl]piperazin-1-yl}-2-oxoethyl)-2-iodopyridine-4-carboxamide 
• 1333316-46-3 N-{2-[4-(5-benzyloxy-pyrimidin-2-yl)-piperazin-1-yl]-2-oxo-ethyl}-2-iodopyridine-4-carboxamide 
• 1086379-95-4 2-(furan-2-yl)isonicotinic acid 
• 29840-76-4 2-iodoisonicotinamide 
• 588702-68-5 2-trifluoromethyl-isonicotinic acid methyl ester 

Relevant articles and documents

HYDRAZONE DERIVATIVE

A compound represented by the following formula (I): wherein R1 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R2 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R3 represents hydrogen, etc.; Ar represents a divalent group derived from aromatic hydrocarbon, etc.; X represents a single bond, linear or branched alkylene having from 1 to 3 carbon atoms which may have a substituent, etc.; and G represents halogen, a saturated or unsaturated 5- or 6-membered cyclic hydrocarbon group which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc., a salt thereof or a solvate thereof; and an agent for inhibiting aggregation and/or deposition of an amyloid protein or an amyloid-like protein, which comprises the compound, a salt thereof or a solvate thereof

Imidazole derivatives

Novel imidazole derivatives are disclosed. These compounds have a good affinity to the NMDA (N-methyl-D-aspartate)-receptor subtype selective blockers, which have a key function in modulating neuronal activity and plasticity which makes them key players in mediating processes underlying development of CNS as well as learning and memory formation. These compounds are useful in the control or treatment of diseases mediated by this receptor.