59207-23-7

Basic information

• Product Name: 2-METHYLTHIENO[3,2-C]PYRIDIN-4(5H)-ONE
• Synonyms: 2-METHYLTHIENO[3,2-C]PYRIDIN-4(5H)-ONE;2-methyl-5H-thieno[3,2-c]pyridin-4-one;2-Methylthieno[3,2-c]pyridin-4(5H)
• CAS NO: 59207-23-7
• Molecular Formula: C8H7NOS
• Molecular Weight: 165.22
• Mol File: 59207-23-7.mol

Chemical Properties

• Boiling Point: 415.8 °C at 760 mmHg
• Flash Point: 205.3 °C
• Appearance: /
• Density: 1.292
• Vapor Pressure: 4.01E-07mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 13.00±0.20(Predicted)
• CAS DataBase Reference: 2-METHYLTHIENO[3,2-C]PYRIDIN-4(5H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLTHIENO[3,2-C]PYRIDIN-4(5H)-ONE(59207-23-7)
• EPA Substance Registry System: 2-METHYLTHIENO[3,2-C]PYRIDIN-4(5H)-ONE(59207-23-7)

Safety Data

• Hazardous Substances Data: 59207-23-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-methylthieno[3,2-c]pyridin-4(5H)-one is employed as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its unique structure and potential biological activity make it a valuable component in the development of new drugs and pesticides.
Used in Organic Chemistry:
In the field of organic chemistry, 2-methylthieno[3,2-c]pyridin-4(5H)-one serves as a building block for the synthesis of more complex molecules. Its versatile structure allows for the creation of a wide range of organic compounds with diverse properties and applications.
Used as a Reagent in Organic Synthesis:
2-methylthieno[3,2-c]pyridin-4(5H)-one is also utilized as a reagent in organic synthesis. It aids in the preparation of various organic compounds, contributing to the advancement of chemical research and the development of new materials and products.

InChI:InChI=1/C8H7NOS/c1-5-4-6-7(11-5)2-3-9-8(6)10/h2-4H,1H3,(H,9,10)

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 14770-88-8 3-(5-methylthiophen-2-yl)acrylic acid 
• 70329-36-1 (E)-3-(5-methyl-2-thienyl)-2-propenoic caid 
• 59207-21-5 (E)-3-(5-Methyl-thiophen-2-yl)-acryloyl chloride 
• 59207-22-6 C₈H₇N₃OS 
• 13679-70-4 5-methylthiophene-2-carboxaldehyde 

Downstream Products

• 1472655-07-4 C₂₉H₂₇NO₅S₂ 
• 1472655-06-3 C₂₉H₂₇NO₆S 
• 59207-24-8 4-Chloro-2-methyl-thieno[3,2-c]pyridine 

Relevant articles and documents

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A 3D-printed polypropylene (PP) continuous-photoflow cell based on a modular cartridge system was developed for the photo-oxygenation of 7-aminothieno[3,2-c]pyridin-4(5H)-ones, using ambient air as the sole co-reactant. This strategy takes advantage of the versatility of 3D-printing to construct cost-effective meso-scale reactors. In addition to scalability, a short residence time (tR 2 min) in 100-W blue LED light that minimizes the formation of dark, insoluble decomposition products is a tangible benefit of this technology.

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A METHOD FOR THE SITE-SPECIFIC ENZYMATIC LABELLING OF NUCLEIC ACIDS IN VITRO BY INCORPORATION OF UNNATURAL NUCLEOTIDES

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Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications

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SUBSTITUTED HETEROCYCLES AND THEIR USE AS CHK1, PDK1 AND PAK INHIBITORS

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1-SUBSTITUTED AMINO-3-THIENO-[3,2-c]PYRIDINYLOXY-2-PROPANOLS

This invention provides new compounds of formula I, STR1 wherein X is sulphur or oxygen,R is alkyl of 3 to 7 carbon atoms or cycloalkyl of 3 to 7 carbon atoms, cycloalkyl of 3 to 7 carbon atoms monosubstituted by alkyl of 1 to 4 carbon atoms, α-dialkylpropinyl of 5 to 9 carbon atoms or α-dialkyl-allyl of 5 to 9 carbon atoms, hydroxyalkyl of 2 to 7 carbon atoms or phenoxyalkyl of 8 to 11 carbon atoms, the oxygen atom of the last two radicals being separated by at least two carbon atoms from the nitrogen atom to which R is bound, R 1 isI. hydrogen or alkyl of 1 to 4 carbon atoms in the 2,3,6 or 7 position, orIi. chlorine or bromine, in the 2, 3 or 7 position,Iii. nitro or--NHA wherein A is alkanoyl of 1 to 4 carbon atoms, in the 2, 3 or 7 position, orIv. fluorine, cyano or COOB, wherein B is alkyl of 1 to 4 carbon atoms, in the 2 or 3 position, andR 2 isI. hydrogen or alkyl of 1 to 4 carbon atoms in the 2, 3, 6 or 7 position,Ii. chlorine or bromine, in the 2, 3 or 7 position, orIii. fluorine in the 2 or 3 position,Useful in the treatment of heart diseases.