59229-63-9

Basic information

• Product Name: 3,3-Dimethylmorpholine
• Synonyms: 3,3-Dimethylmorpholine;3,3-Dimethylmorpholine HCl;morpholine, 3,3-dimethyl-;ethyl 6-broMo-1H-indole-3-carboxylate
• CAS NO: 59229-63-9
• Molecular Formula: C₆H₁₃NO
• Molecular Weight: 115.18
• Product Categories: pharmacetical
• Mol File: 59229-63-9.mol

Chemical Properties

• Boiling Point: 143-144℃
• Flash Point: 47.308°C
• Appearance: /
• Density: 0.873g/cm³
• Vapor Pressure: 5.128mmHg at 25°C
• Refractive Index: 1.4472 (589.3 nm 20℃)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 9.09±0.40(Predicted)
• CAS DataBase Reference: 3,3-Dimethylmorpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-Dimethylmorpholine(59229-63-9)
• EPA Substance Registry System: 3,3-Dimethylmorpholine(59229-63-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 59229-63-9(Hazardous Substances Data)

Usage

Uses

Used in Solvent Applications:
3,3-Dimethylmorpholine is used as a solvent for high-temperature reactions due to its high boiling point and low vapor pressure, making it effective in dissolving a wide range of substances.
Used in Pharmaceutical and Agrochemical Synthesis:
3,3-Dimethylmorpholine is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new and improved products in these industries.
Used as a Catalyst in Organic Reactions:
3,3-Dimethylmorpholine is utilized as a catalyst in various organic reactions, enhancing the efficiency and selectivity of these processes.
Used in Industrial Processes as a Corrosion Inhibitor:
3,3-Dimethylmorpholine is employed as a corrosion inhibitor in industrial processes, protecting equipment and infrastructure from the damaging effects of corrosion.
Used in Chemical Industry:
3,3-Dimethylmorpholine is used as a versatile chemical in the chemical industry for its wide range of applications, including solvent, catalyst, and intermediate roles.
Used in Research and Development:
3,3-Dimethylmorpholine is utilized in research and development for its potential applications in various fields, such as the development of new materials, pharmaceuticals, and agrochemicals.

InChI:InChI=1/C6H13NO/c1-6(2)5-8-4-3-7-6/h7H,3-5H2,1-2H3

Upstream product

• 28228-40-2 2-Chloro-N-(2-hydroxy-1,1-dimethyl-ethyl)-acetamide 
• 127958-62-7 5,5-dimethylmorpholin-3-one 
• 70787-40-5 2-[(2-hydroxyethyl)amino]-2-methylpropan-1-ol 

Downstream Products

• 1600527-96-5 (3,3-dimethyl-morpholin-4-yl)-[5-(3-chloro-phenylethynyl)-pyrimidin-2-yl]-methanone 
• 1600527-93-2 (3,3-dimethyl-morpholin-4-yl)-[5-(3-fluoro-phenylethynyl)-pyridin-2-yl]-methanone 
• 1445589-44-5 methyl ((S)-1-((S)-2-(5-(4-(2-((1S,2S)-2-(3,3-dimethylmorpholine-4-carbonyl)cyclopentyl)-1H-imidazol-5-yl)-[1,1‘-biphenyl]-4-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate 
• 1355003-96-1 3,3-dimethyl-4-({1-[3-(trifluoromethyl)phenyl]-1H-tetrazol-5-yl}methyl)morpholine 
• 1355004-06-6 4-{5-[(3,3-dimethyl-4-morpholinyl)methyl]-1H-tetrazol-1-yl}benzonitrile 

Relevant articles and documents

A concise and efficient synthesis of substituted morpholines

A simple and efficient method has been developed for the synthesis of substituted morpholines by a sequence of coupling, cyclization, and reduction reactions of easily available amino alcohols and α-halo acid chlorides. Various mono-, di-, and trisubstituted morpholines, spiro morpholines, and ring-fused morpholines, as well as morpholine homologues, were synthesized in good to excellent yields by a single methodology under similar reaction conditions. The method was also used in a multigram synthesis of (3S)-3-methylmorpholine.

Beta-carbolines useful for treating inflammatory disease

This invention provides beta-carboline compounds of formula III-A-aa: wherein Q, G, R1, R2, R3, and R6b are as described in the specification. The compounds are useful for treating diseases such as inflammatory diseases and cancer.