596817-02-6

Basic information

• Product Name: 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-4,4-difluoro-, (2S)- (9CI)
• Synonyms: 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-4,4-difluoro-, (2S)- (9CI)
• CAS NO: 596817-02-6
• Molecular Formula: C₇H₇ClF₂N₂O
• Molecular Weight: 208.5930864
• Product Categories: ACETYLHALIDE
• Mol File: 596817-02-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-4,4-difluoro-, (2S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-4,4-difluoro-, (2S)- (9CI)(596817-02-6)
• EPA Substance Registry System: 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-4,4-difluoro-, (2S)- (9CI)(596817-02-6)

Safety Data

• Hazardous Substances Data: 596817-02-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-4,4-difluoro-, (2S)(9CI) is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structural features, including the chloroacetyl and difluoromethyl groups, may contribute to the development of new therapeutic agents with novel mechanisms of action.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-4,4-difluoro-, (2S)(9CI) may serve as a key intermediate in the production of agrochemicals, such as pesticides and herbicides. Its specific stereochemistry and functional groups could potentially enhance the efficacy and selectivity of these products, leading to improved agricultural outcomes.
Further research is necessary to fully explore the specific uses and potential benefits of 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-4,4-difluoro-, (2S)(9CI) in various industries, as its unique structural features and properties may offer new opportunities for innovation and development.

Upstream product

• 483366-15-0 (S)-4,4-difluoropyrrolidine-2-carbonitrile 
• 79-04-9 chloroacetyl chloride 
• 596817-01-5 (2S)-1-(2-chloroacetyl)-4,4-difluoro-2-pyrrolidine-carboxamide 

Relevant articles and documents

PYRROLIDINE AND PIPERIDINE COMPOUNDS

The present technology provides pyrrolidine and piperidine compounds or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. In particular, said compounds may be usefully applied in the treatment and prevention of FAP-mediated diseases.

Discovery of conformationally rigid 3-azabicyclo[3.1.0]hexane-derived dipeptidyl peptidase-IV inhibitors

The induction of conformationally restricted N-(aryl or heteroaryl)-3-azabicyclo[3.1.0]hexane derivatives at P2 region of compounds of 2-cyanopyrrolidine class was explored to develop novel DPP-IV inhibitors. The synthesis, structure-activity r

NEW COMPOUNDS

The invention relates to new compounds of the general formula (I), which are strong DPP-IV enzyme inhibitors.

2-CYANOPYRROLIDINE DERIVATIVES AND THEIR USE AS DPP-IV INHIBITORS

A compound of the formula (I) or a pharmaceutically acceptable salt thereof: [wherein X is CFH, or CF?2#191, R?1? is the moiety represented by the formula: [wherein R?2? is (lower) alkyl, R?3? is phenyl-(lower)alkyl, and the like.], and the like.] Compounds of formula (I) inhibit DPP-IV activity. They are therefore useful in the treatment of conditions mediated by DPP-IV, such as NIDDM.

NEW COMPOUNDS

The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.