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(4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-hydroxypentanoic acid ethyl ester is a chemical compound with the molecular formula C12H23NO5. It is an ethyl ester derivative of (4R)-4-aminoglutamic acid, a naturally occurring amino acid. (4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-hydroxypentanoic acid ethyl ester is characterized by its ethyl ester group, hydroxy and amino functionalities, and is known for its versatility in organic synthesis and pharmaceutical research.

597577-78-1

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597577-78-1 Usage

Uses

Used in Organic Synthesis:
(4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-hydroxypentanoic acid ethyl ester is used as a building block in organic synthesis for its ability to be easily modified to introduce various functional groups. This makes it a valuable intermediate for the creation of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-hydroxypentanoic acid ethyl ester is used as a versatile precursor for the synthesis of bioactive compounds and pharmaceuticals. Its presence of a hydroxy and amino group allows for the development of new drugs with potential therapeutic applications.
Used to Improve Solubility and Handling:
The ethyl ester group in (4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-hydroxypentanoic acid ethyl ester allows for better solubility and handling of the compound in organic solvents, which is advantageous in chemical reactions and purification processes.

Check Digit Verification of cas no

The CAS Registry Mumber 597577-78-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,7,5,7 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 597577-78:
(8*5)+(7*9)+(6*7)+(5*5)+(4*7)+(3*7)+(2*7)+(1*8)=241
241 % 10 = 1
So 597577-78-1 is a valid CAS Registry Number.

597577-78-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl (4R)-5-hydroxy-4-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:597577-78-1 SDS

597577-78-1Relevant articles and documents

Discovery of a novel EP2/EP4 dual agonist with high subtype-selectivity

Kambe, Tohru,Maruyama, Toru,Nakano, Masayuki,Nakai, Yoshihiko,Yoshida, Tadahiro,Matsunaga, Naoki,Oida, Hiroji,Konaka, Akira,Maruyama, Takayuki,Nakai, Hisao,Toda, Masaaki

scheme or table, p. 396 - 401 (2012/02/16)

A series of γ-lactam prostaglandin E1 analogs bearing a 16-phenyl moiety in the ω-chain and aryl moiety in the α-chain were synthesized and biologically evaluated. Among the tested compounds, γ-lactam PGE analog 3 designed as a structural hybrid of 1 and 2 was discovered as the most optimized EP2/EP4 dual agonist with excellent subtype-selectivity (Ki values: mEP2 = 9.3 nM, mEP4 = 0.41 nM). A structure-activity relationship study is presented.

INDOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS

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Page/Page column 21, (2010/08/22)

The present invention relates to new indole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole compounds as an active ingredient.

INDOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS

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Page/Page column 68, (2009/04/25)

The present invention relates to new indole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole compounds as an active ingredient.

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