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Pterodondiol, a naturally occurring diterpenoid compound found in the plant Pterodon emarginatus, has garnered attention for its potential medicinal properties. It is known for its anti-inflammatory and analgesic effects, positioning it as a promising candidate for the treatment of pain and inflammation-related conditions. Moreover, Pterodondiol has demonstrated potential anti-cancer activity in preclinical studies, contributing to its significance in ongoing research for the development of new therapeutic agents.

60132-35-6

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60132-35-6 Usage

Uses

Used in Pharmaceutical Industry:
Pterodondiol is used as an anti-inflammatory and analgesic agent for its ability to alleviate pain and reduce inflammation, making it a potential treatment for various pain and inflammation-related conditions.
Used in Oncology Research:
Pterodondiol is used as a potential anti-cancer agent in preclinical studies, where it has shown promise in targeting and inhibiting cancer cell growth, thus contributing to the development of novel cancer therapeutics.
Used in Drug Development:
Pterodondiol is utilized in the ongoing research and development of new therapeutic agents due to its diverse pharmacological properties, which include anti-inflammatory, analgesic, and potential anti-cancer effects. This makes it a valuable compound for creating innovative treatments in the pharmaceutical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 60132-35-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,1,3 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 60132-35:
(7*6)+(6*0)+(5*1)+(4*3)+(3*2)+(2*3)+(1*5)=76
76 % 10 = 6
So 60132-35-6 is a valid CAS Registry Number.

60132-35-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Pterodondiol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:60132-35-6 SDS

60132-35-6Downstream Products

60132-35-6Relevant articles and documents

Short and efficient hemisynthesis of α-eudesmol and cryptomeridiol

Tebbaa, Mohamed,El Hakmaoui, Ahmed,Benharref, Ahmed,Akssira, Mohamed

, p. 3769 - 3771 (2011/08/06)

The aerial part of Dittrichia viscosa yielded two sesquiterpenes, isocostic acid (1) and ilicic acid (2), on multigram scale. These acids are appropriate starting materials for short and facile syntheses of α-eudesmol (5) and cryptomeridiol (6), natural products featuring anti-Alzheimer and anti-spasmodic properties. Compounds 5 and 6 were obtained in three steps in overall yields of 70% and 52%, respectively.

Enantioselective total syntheses of (-)-7βH-eudesmane-4α,11-diol and (+)-ent-7βH-eudesmane-4α,11-diol

Shimoma, Fumito,Kondo, Hisao,Yuuya, Saori,Suzuki, Toshio,Hagiwara, Hisahiro,Ando, Masayoshi

, p. 22 - 28 (2007/10/03)

The syntheses of (-)-7βH-eudesmane-4α,11-diol (2) and (+)-ent-7βH- eudesmane-4α,11-diol (ent2) were carried out starting from (-)- and (+)- dihydrocarvones. As a result, the structure, including absolute configuration, of the naturally occurring eudesmane-4,11-diol isolated from Pluchea arguta was determined to be (+)-ent-7βH-eudesmane-4α,11-diol (ent- 2).

Structures and spasmolytic activities of derivatives from sesquiterpenes of Alpinia speciosa and Alpinia japonica

Morita, Makoto,Nakanishi, Hiroshi,Morita, Hiroshi,Mihashi, Susumu,Itokawa, Hideji

, p. 1603 - 1606 (2007/10/03)

Sesquiterpenes isolated from Alpinia speciosa and Alpinia japonica, and their derivatives were found to inhibit histamine- or barium chloride- induced contraction of excised guinea pig ileum when tested by the Magnus method. Major spasmolytic principles contained in those extracts were the sesquiterpenes, β-eudesmol, nerolidol, humulene epoxide II and 4α- hydroxydihydroagarofuran. Relationships between the chemical structures of the sesquiterpenes and their derivatives, and their spasmolytic activities were discussed.

SESQUITERPENES FROM LEAVES OF CRYPTOMERIA JAPONICA

Su, Wen-Chiung,Fang, Jim-Min,Cheng, Yu-Shia

, p. 603 - 608 (2007/10/02)

Twenty-seven sesquiterpenes were isolated from leaves of Cryptomeria japonica.The new compounds included elem-1-en-4,11-diol, 11-acetoxyeudesman-4α-ol, eudesmane-5α,11-diol, 3-eudesmene-1β,11-diol, 1β-acetoxy-3-eudesmen-11-ol, 4-eudesmene-1β,11-diol, 1β-acetoxy-4-eudesmen-11-ol, 7-epi-4-eudesmene-1β,11-diol, 1β-acetoxy-4(15)eudesmen-11-ol.Their structures were determined by chemical and spectral methods. - Key words: Cryptomeria japonica; Taxodiaceae; leaves; sesquiterpenes.

Biotransformation of (+/-)-4,8-dimethylcyclodeca-3(E),7(E)-dien-1β-ol and (+)-Hedycaryol by Cichorium intybus

Piet, Dennis P.,Minnaard, Adriaan J.,Heyden, Karel A. van der,Franssen, Maurice C. R.,Wijnberg, Joannes B. P. A.,Groot, Aede de

, p. 243 - 254 (2007/10/02)

The biotransformation of the synthetic (E,E)-1,5-cyclodecadienol 5 and (+)-hedycaryol (11) by a root suspension of fresh chicory has been investigated.Incubation of 5 with a root suspension gave a 2:1 mixture of epimeric eudesmanediols 7a and 7b whereas 11 was selectively converted into cryptomeridiol (12).An explanation for the obtained results is proposed.

Structures of Eudesmagnolol and Eudeshonokiol, Novel Sesquiterpene-Neolignans Isolated from Magnolia obovata

Fukuyama, Yoshiyasu,Otoshi, Yukio,Nakamura, Kazuhiko,Kodama, Mitsuaki,Sugawara, Michiharu,Nagaswa, Masakazu

, p. 295 - 296 (2007/10/02)

Eudesmagnolol and eudeshonokiol, isolated from the bark of Magnolia obovata, have been assigned to unprecedented structures linked via an ether bond between sesquiterpene, eudesmol, and neolignans, magnolol and honokiol, respectively.

NOVEL NEUROTROPHIC SESQUITERPENE-NEOLIGNANS FROM MAGNOLIA OBOVATA

Fukuyama, Yoshiyasu,Otoshi, Yukio,Kodama, Mitsuaki,Hasegawa, Takashi,Okazaki, Hiroshi,Nagasawa, Masakazu

, p. 5907 - 5910 (2007/10/02)

Novel sesquiterpene-neolignans, eudesobovatols A (1) and B (2) isolated from Magnolia obovata have been assigned structures on the basis of detailed spectroscopic analyses and chemical degradation, and eudesobovatol A has been found to exhibit neurotrophic activity at 1E-5 M 1E-7 M on neuronal cell culture system of fetal rat cerebral hemisphere.

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