60549-26-0

Basic information

• Product Name: 3-Hydroxy-5-Methylbenzaldehyde
• Synonyms: 3-Hydroxy-5-Methylbenzaldehyde
• CAS NO: 60549-26-0
• Molecular Formula: C₈H₈O₂
• Molecular Weight: 136.14792
• Mol File: 60549-26-0.mol

Chemical Properties

• Melting Point: 107-108 °C(Solv: chloroform (67-66-3))
• Boiling Point: 259.2±20.0 °C(Predicted)
• Appearance: /
• Density: 1.175±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 9.35±0.10(Predicted)
• CAS DataBase Reference: 3-Hydroxy-5-Methylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxy-5-Methylbenzaldehyde(60549-26-0)
• EPA Substance Registry System: 3-Hydroxy-5-Methylbenzaldehyde(60549-26-0)

Safety Data

• Hazardous Substances Data: 60549-26-0(Hazardous Substances Data)

Usage

Uses

Used in Flavor and Fragrance Industry:
3-Hydroxy-5-Methylbenzaldehyde is used as a flavoring agent for imparting distinctive vanilla and almond flavors to food products. Its unique aromatic properties make it a valuable ingredient in the food industry, enhancing the taste and aroma of a variety of dishes and confectioneries.
Used in Perfumery:
In the perfume industry, 3-Hydroxy-5-Methylbenzaldehyde is utilized as a fixative and scent component. Its sweet, aromatic scent contributes to the longevity and complexity of perfumes, making it an essential component in creating long-lasting and appealing fragrances.
Used in Pharmaceutical Synthesis:
3-Hydroxy-5-Methylbenzaldehyde serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. Its chemical properties allow it to be a key building block in the development of new drugs, playing a significant role in the advancement of medicinal chemistry.
Used in Chemical Industry:
As an important intermediate in the chemical industry, 3-Hydroxy-5-Methylbenzaldehyde is involved in the production of a range of chemical products. Its versatility in chemical reactions makes it a valuable component in the synthesis of various compounds used across different sectors.

Upstream product

• 90674-26-3 3-methoxy-5-methyl-benzaldehyde 
• 119650-44-1 (3-methoxy-5-methylphenyl)methanol 
• 106116-42-1 1-bromomethyl-3-methoxy-5-methyl-benzene 
• 90003-09-1 2-Chloro-5-methylcyclohex-1-en-1-carbaldehyd 

Downstream Products

• 329788-96-7 2-(3-hydroxy-5-methylphenyl)-1,3-dioxane 
• 90674-26-3 3-methoxy-5-methyl-benzaldehyde 

Relevant articles and documents

NOVEL METAL FREE PROCESS FOR ALLYLIC OXIDATION

The patent discloses a novel metal free process for the preparation of corresponding phenol and ketone via allylic oxidation of substituted cyclohexenes. Air is used as oxidant in the present process and can be used as such or optionally selected from pure oxygen or atmospheric oxygen. Moreover, the process of the present invention utilizes easily available starting materials and is a green eco-friendly, convenient and economical process with high yield of >60 % and high selectivity

Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway

Two enzymes of the gilvocarcin biosynthetic pathway, GilMT and GilM, with unclear functions were investigated by in vitro studies using purified, recombinant enzymes along with synthetically prepared intermediates. The studies revealed GilMT as a typical