- Synthesis of 6-(N-azolyl)cyclohex-2-enones from N-acetonylazoles
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N-Acetonylazoles react with chalcones in the presence of a base to give trans-3,5-disubstituted 6-(N-azolyl)cyclohex-2-enones. Usually, the reactions are fast and high-yielding.
- Samet,Yamskov,Kachala,Semenov
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p. 552 - 556
(2007/10/03)
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- Oxidation of Amino Derivatives of 1,2,4-Triazole
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Derivatives of 3-nitro-5-R-1,2,4-triazoles are prepared by oxidation of the corresponding amino-compounds in the system 30% hydrogen peroxide - sodium tungstate. The activity of aminotriazoles decreases with increasing electronacceptor ability. For substrates unsubstituted at the heteroatom the process is promoted by bases. 3,5-Diamino-1,2,4-triazole is oxidized in two steps, and substantial difference in the rates of of the first and second stages of oxidation yielding respectively (5-amino-3-nitro- and 3,5-dinitro-1,2,4-triazole allows isolation of the former in up to 60% yield. N,N′-Azoxy-3,3′-bis(5-amino-1,2,4-triazole) is formed as a by-product. In 1-substituted 3,5-diaminotriazoles only one, peripheral, amino group is oxidized to afford derivatives of 5-amino-3-nitro-1,2,4-triazole.
- Kofman,Paketina
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p. 1125 - 1132
(2007/10/03)
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- INVESTIGATION OF THE ALKYLATION OF NITROAZOLES WITH α-HALOKETONES BY 13C, 15N, AND 14N NMR
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General methods have been worked out for the alkylation of nitroazoles with bromoacetone, bromoacetophenone, and diazoacetone in homogenous media and by phase-transfer catalysis.The structures of the N-acetonylazoles were established by 13C, 15N, and 14N
- Semenov, V. V.,Ugrak, B. I.,Shevelev, S. A.,Kanishchev, M. I.,Baryshnikov, A. T.,Fainzil'berg, A. A.
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p. 1658 - 1666
(2007/10/02)
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