60728-89-4 Usage
Uses
Used in Pharmaceutical Industry:
1-(3-NITRO-1H-1,2,4-TRIAZOL-1-YL)ACETONE is used as an intermediate for the synthesis of various pharmaceuticals. Its ability to act as a versatile building block allows for the creation of complex molecules, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(3-NITRO-1H-1,2,4-TRIAZOL-1-YL)ACETONE is utilized as an intermediate in the synthesis of different agrochemicals. Its role in building complex molecules aids in the development of innovative products for agricultural applications, such as pesticides and fertilizers.
Used in Organic Chemistry:
1-(3-NITRO-1H-1,2,4-TRIAZOL-1-YL)ACETONE is employed as a key intermediate in organic chemistry for the synthesis of a wide range of organic compounds. Its versatility in forming complex molecules makes it a valuable component in the development of new materials and chemical products.
Used in Research and Development:
1-(3-NITRO-1H-1,2,4-TRIAZOL-1-YL)ACETONE is also used in research and development settings, where it serves as a starting material for the exploration of new chemical reactions and the synthesis of novel molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 60728-89-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,7,2 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 60728-89:
(7*6)+(6*0)+(5*7)+(4*2)+(3*8)+(2*8)+(1*9)=134
134 % 10 = 4
So 60728-89-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N4O3/c1-4(10)2-8-3-6-5(7-8)9(11)12/h3H,2H2,1H3
60728-89-4Relevant academic research and scientific papers
Synthesis of 6-(N-azolyl)cyclohex-2-enones from N-acetonylazoles
Samet,Yamskov,Kachala,Semenov
, p. 552 - 556 (2007/10/03)
N-Acetonylazoles react with chalcones in the presence of a base to give trans-3,5-disubstituted 6-(N-azolyl)cyclohex-2-enones. Usually, the reactions are fast and high-yielding.
Oxidation of Amino Derivatives of 1,2,4-Triazole
Kofman,Paketina
, p. 1125 - 1132 (2007/10/03)
Derivatives of 3-nitro-5-R-1,2,4-triazoles are prepared by oxidation of the corresponding amino-compounds in the system 30% hydrogen peroxide - sodium tungstate. The activity of aminotriazoles decreases with increasing electronacceptor ability. For substrates unsubstituted at the heteroatom the process is promoted by bases. 3,5-Diamino-1,2,4-triazole is oxidized in two steps, and substantial difference in the rates of of the first and second stages of oxidation yielding respectively (5-amino-3-nitro- and 3,5-dinitro-1,2,4-triazole allows isolation of the former in up to 60% yield. N,N′-Azoxy-3,3′-bis(5-amino-1,2,4-triazole) is formed as a by-product. In 1-substituted 3,5-diaminotriazoles only one, peripheral, amino group is oxidized to afford derivatives of 5-amino-3-nitro-1,2,4-triazole.
INVESTIGATION OF THE ALKYLATION OF NITROAZOLES WITH α-HALOKETONES BY 13C, 15N, AND 14N NMR
Semenov, V. V.,Ugrak, B. I.,Shevelev, S. A.,Kanishchev, M. I.,Baryshnikov, A. T.,Fainzil'berg, A. A.
, p. 1658 - 1666 (2007/10/02)
General methods have been worked out for the alkylation of nitroazoles with bromoacetone, bromoacetophenone, and diazoacetone in homogenous media and by phase-transfer catalysis.The structures of the N-acetonylazoles were established by 13C, 15N, and 14N
