- Vicarious Nucleophilic Chloromethylation of Nitroaromatics
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Nitroaromatics substituted with electron-acceptor or electron-donor groups undergo vicarious nucleophilic substitution with the lithium salt of dichloromethane to provide chloromethyl-substituted nitroaromatics in good to high yields. The methodology represents a new strategy for the synthesis of benzyl chlorides.
- Khutorianskyi, Viktor V.,Klepetá?ová, Blanka,Beier
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supporting information
p. 5443 - 5446
(2019/07/03)
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- Highly efficient dinitration of aromatic compounds in fluorous media using ytterbium perfluorooctanesulfonate and perfluorooctanesulfonic acid as catalysts
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Ytterbium perfluorooctanesulfonate [Yb(OPf)3] and perfluorooctanesulfonic acid [PfOH] catalyze the highly efficient dinitration of toluene, benzene, benzyl chloride, and chlorobenzene in fluorous media. Notably the process produces almost no waste acid, as opposed to the traditional case. The fluorous phase-containing catalyst could be easily and efficiently recovered for reuse by simple phase separation. Copyright Taylor & Francis Group, LLC.
- Yi, Wen-Bin,Cai, Chun
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p. 2957 - 2961
(2007/10/03)
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