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2,4-Dinitrobenzyl chloride, with the chemical formula C7H4ClNO4, is a yellow crystalline solid that serves as a crucial chemical compound in the field of organic synthesis. It is primarily recognized for its role as a protecting group for alcohols and amines, ensuring that these functional groups remain intact and unreacted during chemical reactions. This property makes 2,4-dinitrobenzyl chloride an indispensable component in the synthesis of pharmaceuticals, dyes, and a variety of other organic compounds. Due to its high reactivity and potential toxicity, it is essential to handle 2,4-DINITROBENZYL CHLORIDE with caution to avoid skin and eye irritation.

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  • 610-57-1 Structure
  • Basic information

    1. Product Name: 2,4-DINITROBENZYL CHLORIDE
    2. Synonyms: 1-(CHLOROMETHYL)-2,4-DINITROBENZENE;2-Chloro-2,4-dinitrotoluene;2,4-DINITROBENZYL CHLORIDE;ALPHA-CHLORO-2,4-DINITROTOLUENE;LABOTEST-BB LT00159954;2,4-Dinitrobenzyl chloride, 98+%;Benzene, 1-(chloromethyl)-2,4-dinitro-;à-chloro-2,4-dinitrotoluene
    3. CAS NO:610-57-1
    4. Molecular Formula: C7H5ClN2O4
    5. Molecular Weight: 216.58
    6. EINECS: 210-230-5
    7. Product Categories: N/A
    8. Mol File: 610-57-1.mol
  • Chemical Properties

    1. Melting Point: 34-36 °C(lit.)
    2. Boiling Point: 349.8 °C at 760 mmHg
    3. Flash Point: >230 °F
    4. Appearance: /
    5. Density: 1.538 g/cm3
    6. Vapor Pressure: 9.24E-05mmHg at 25°C
    7. Refractive Index: 1.614
    8. Storage Temp.: Store below +30°C.
    9. Solubility: N/A
    10. CAS DataBase Reference: 2,4-DINITROBENZYL CHLORIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,4-DINITROBENZYL CHLORIDE(610-57-1)
    12. EPA Substance Registry System: 2,4-DINITROBENZYL CHLORIDE(610-57-1)
  • Safety Data

    1. Hazard Codes: C
    2. Statements: 34-36/37
    3. Safety Statements: 26-27-28-36/37/39-45
    4. RIDADR: UN 3261 8/PG 2
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: 8
    8. PackingGroup: III
    9. Hazardous Substances Data: 610-57-1(Hazardous Substances Data)

610-57-1 Usage

Uses

Used in Organic Synthesis:
2,4-Dinitrobenzyl chloride is used as a protecting group in organic synthesis for the purpose of preventing unwanted reactions or side reactions involving alcohols and amines. This ensures that the desired products are obtained without the interference of undesired byproducts, thereby enhancing the efficiency and selectivity of the synthesis process.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2,4-dinitrobenzyl chloride is utilized as a key intermediate in the synthesis of various drugs. Its ability to protect functional groups during chemical reactions allows for the creation of complex molecular structures with greater precision and control, ultimately leading to the development of more effective and safer medications.
Used in Dye Manufacturing:
2,4-DINITROBENZYL CHLORIDE also finds application in the production of dyes, where it is employed as a protecting group to facilitate the synthesis of colorants with specific properties. By preventing unwanted reactions during the dye synthesis process, 2,4-dinitrobenzyl chloride contributes to the production of dyes with improved colorfastness, stability, and performance in various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 610-57-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 0 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 610-57:
(5*6)+(4*1)+(3*0)+(2*5)+(1*7)=51
51 % 10 = 1
So 610-57-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClN2O4/c8-4-5-1-2-6(9(11)12)3-7(5)10(13)14/h1-3H,4H2

610-57-1 Well-known Company Product Price

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  • Aldrich

  • (307262)  2,4-Dinitrobenzylchloride  99%

  • 610-57-1

  • 307262-1G

  • 458.64CNY

  • Detail
  • Aldrich

  • (307262)  2,4-Dinitrobenzylchloride  99%

  • 610-57-1

  • 307262-10G

  • 2,335.32CNY

  • Detail

610-57-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(chloromethyl)-2,4-dinitrobenzene

1.2 Other means of identification

Product number -
Other names EINECS 210-230-5

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:610-57-1 SDS

610-57-1Relevant articles and documents

Vicarious Nucleophilic Chloromethylation of Nitroaromatics

Khutorianskyi, Viktor V.,Klepetá?ová, Blanka,Beier

supporting information, p. 5443 - 5446 (2019/07/03)

Nitroaromatics substituted with electron-acceptor or electron-donor groups undergo vicarious nucleophilic substitution with the lithium salt of dichloromethane to provide chloromethyl-substituted nitroaromatics in good to high yields. The methodology represents a new strategy for the synthesis of benzyl chlorides.

Highly efficient dinitration of aromatic compounds in fluorous media using ytterbium perfluorooctanesulfonate and perfluorooctanesulfonic acid as catalysts

Yi, Wen-Bin,Cai, Chun

, p. 2957 - 2961 (2007/10/03)

Ytterbium perfluorooctanesulfonate [Yb(OPf)3] and perfluorooctanesulfonic acid [PfOH] catalyze the highly efficient dinitration of toluene, benzene, benzyl chloride, and chlorobenzene in fluorous media. Notably the process produces almost no waste acid, as opposed to the traditional case. The fluorous phase-containing catalyst could be easily and efficiently recovered for reuse by simple phase separation. Copyright Taylor & Francis Group, LLC.

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