- Co(III)-Catalyzed Synthesis of Quinazolines via C-H Activation of N-Sulfinylimines and Benzimidates
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C-H activation of arenes has been established as an important strategy for heterocycle synthesis via annulations between arenes and unsaturated coupling partners. However, nitriles failed to act as such a coupling partner. Dioxazolones have been employed as a synthon of nitriles, and subsequent coupling with arenes such as N-sulfinylimines and benzimidates bearing a functionalizable directing group provided facile access to two classes of quinazolines under Co(III)-catalysis.
- Wang, Fen,Wang, He,Wang, Qiang,Yu, Songjie,Li, Xingwei
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supporting information
p. 1306 - 1309
(2016/04/01)
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- Difluoroboroxymolybdenum fischer carbene complexes as precursors of acyl radicals: Dimerization and trapping with electron-deficient alkenes
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Pentacarbonyl acyl molybdates 1 react with boron trifluoride to give difluoroboroxy Fischer carbene complexes 2, which undergo loss of the metal fragment at room temperature to form 1,2-diketones 3, 1,2-hydroxy ketones 4, or dimers 5 through a dimerization or decarbonylation-dimerization process of acyl radicals. Decomposition of 2 in the presence of electron-deficient alkenes 11 and 18 furnishes the two-, three-, and four-component coupling products 12, 13, 19, 20, and 21.
- Barluenga, Jose,Rodriguez, Felix,Fananas, Francisco J.
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p. 1930 - 1937
(2007/10/03)
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