614750-81-1

Basic information

• Product Name: [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)
• Synonyms: [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI);1,2,4]TRIAZOLO[1,5-A]PYRIDINE-6-CARBOXALDEHYDE;[1,2,4]triazolo[1,5-a]pyridine-6-carbaldehyde;6-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine;6-Formyl-1,2,4-triazolo[1,5-a]pyridine;1,2,4-Triazolo[1,5-a]pyridine-6-carboxaldehyde 97%
• CAS NO: 614750-81-1
• Molecular Formula: C₇H₅N₃O
• Molecular Weight: 147.1341
• EINECS: 1308068-626-2
• Product Categories: ALDEHYDE
• Mol File: 614750-81-1.mol

Chemical Properties

• Melting Point: 156-158
• Appearance: /
• Density: 1.393 g/cm³
• Refractive Index: 1.696
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.57±0.30(Predicted)
• CAS DataBase Reference: [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)(614750-81-1)
• EPA Substance Registry System: [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)(614750-81-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 614750-81-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) serves as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) is also utilized as a building block in the creation of agrochemicals, playing a role in the development of pesticides and other agricultural products to enhance crop protection and yield.
Used in Medicinal Chemistry Research:
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) is employed as a research tool in medicinal chemistry, aiding scientists in understanding its interaction with biological targets and exploring its potential as a therapeutic agent.
Used in Drug Discovery:
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) is used in drug discovery processes to identify and optimize new molecular entities with potential applications in treating various diseases, including neurological disorders and cancer.
While the compound has shown promising results in preliminary research, further studies are necessary to fully elucidate its pharmacological properties and establish its safety and efficacy in clinical settings.

InChI:InChI=1/C7H5N3O/c11-4-6-1-2-7-8-5-9-10(7)3-6/h1-5H

Upstream product

• 614750-84-4 6?iodo[1,2,3]triazolo[1,5?a]pyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 75-29-6 isopropyl chloride 
• 1075260-64-8 6-ethenyl[1,2,4]triazolo[1,5-a]pyridine 

Downstream Products

• 614750-82-2 1-(6-methylpyridin-2-yl)-2-[1,2,4]triazolo-[1,5-a]pyridin-6-yl-ethanone 
• 1415663-77-2 diphenyl ([1,2,4]triazolo[1,5-a]pyridin-6-yl(phenylamino)methyl)phosphonate 
• 1415664-13-9 C₂₂H₁₇FN₆S 
• 1415664-11-7 C₂₃H₁₇N₇S 
• 1415664-10-6 C₂₂H₁₈N₆S 
• 1415664-07-1 C₂₄H₂₂N₆O₂S 
• 1415664-06-0 C₂₄H₂₂N₆O₂S 
• 1415664-05-9 C₂₄H₂₂N₆O₂S 
• 1415664-04-8 C₂₄H₂₂N₆S 
• 1415664-03-7 C₂₄H₂₂N₆S 
• 1415664-02-6 C₂₂H₁₆Cl₂N₆S 
• 1415664-01-5 C₂₂H₁₆Cl₂N₆S 
• 1415664-00-4 C₂₂H₁₆Cl₂N₆S 
• 1415663-99-8 C₂₂H₁₆F₂N₆S 

Relevant articles and documents

Synthesis method of [1,2,4]triazole [1,5-A]pyridine-6-carboxaldehyde

Synthesis method of [1,2,4] triazole [1,5-A] pyridine-6-formaldehyde, comprising the following steps: 55-65g magnesium chips, 100ml anhydrous tetrahydrofuran, a small amount of 2-chloropropane and several iodine into a 2L reaction bottle, vacuum replacement nitrogen, stirring, micro-heating initiation of the reaction, after initiation, dropwise add 200-220g2-chloropropane / 1.4L tetrahydrofuran solution, reaction exothermic, tap water insulation T = 45-50 ° C, add room temperature reaction for 2h, standby, The aqueous layer is extracted with 1.5L×2 ethyl acetate, combined organic phase, 2L saturated brine washing, 1000g anhydrous sodium sulfate drying, reduced pressure concentration to dry, to obtain the product, the synthesis method has a highly efficient reaction, fast, mild conditions, simple and easy to obtain substrate, wide applicability, short reaction time, high yield advantages, reasonable route design, simple experimental operation, easy to achieve, and the yield of the obtained product is high.

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