615568-24-6

Basic information

• Product Name: 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde
• Synonyms: 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde;2H,3H-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde
• CAS NO: 615568-24-6
• Molecular Formula: C8H7NO3
• Molecular Weight: 165.147
• Mol File: 615568-24-6.mol

Chemical Properties

• Boiling Point: 293.012ºC at 760 mmHg
• Flash Point: 131.01ºC
• Appearance: /
• Density: 1.34g/cm3
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.595
• PKA: 1.99±0.20(Predicted)
• CAS DataBase Reference: 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde(615568-24-6)
• EPA Substance Registry System: 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde(615568-24-6)

Safety Data

• Hazardous Substances Data: 615568-24-6(Hazardous Substances Data)

Usage

Uses

Used in Diabetes Research:
2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde is used as a diabetogenic agent in scientific research for inducing diabetes in laboratory animals. It is employed to study the mechanisms of pancreatic beta cell damage and to investigate potential treatments for diabetes. The use of alloxan allows researchers to better understand the pathophysiology of diabetes and develop new therapeutic strategies.
Used in the Production of Indigo Dyes:
In the chemical industry, 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde is utilized in the production of indigo dyes. Indigo dyes are widely used in the textile industry for coloring fabrics, and alloxan plays a crucial role in the synthesis process.
Used as a Reagent in Organic Synthesis:
2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde is also used as a reagent in various organic synthesis processes. Its unique chemical properties make it a valuable component in the synthesis of a range of organic compounds, contributing to the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.

InChI:InChI=1/C8H7NO3/c10-5-6-1-2-7-8(9-6)12-4-3-11-7/h1-2,5H,3-4H2

Upstream product

• 615568-23-5 (2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-6-yl)methanol 
• 443955-66-6 2-(2-iodo-6-methylpyridin-3-yloxy)ethanol 
• 1334784-91-6 acetic acid 2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-6-ylmethyl ester 
• 129421-33-6 6-methyl-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine 
• 615568-21-3 6-methyl-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine 5-oxide 
• 1121-78-4 5-Hydroxy-2-methylpyridine 
• 23003-30-7 2-iodo-6-methyl-3-pyridinol 

Downstream Products

• 1095276-23-5 2,3-dihydro[1,4]dioxino[2,3-b]pyridine-6-carboxylic acid 
• 1334784-92-7 2-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-6-yl)acetic acid 

Relevant articles and documents

DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF

The present invention relates to a group of 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3-dihydropyridin-6-one (piperlongumine) derivatives, analogs and pharmaceutically acceptable salts thereof. The present invention also relates to a pharmaceutical composition and formulation containing a derivative of piperlongumine; and use of the derivatives and analogs for treating cancer, reducing inflammation and/or treating an autoimmune or inflammatory disease.

DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF

The present invention relates to a group of 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3- dihydropyridin-6-one (piperlongumine) derivatives, analogs and pharmaceutically acceptable salts thereof. The present invention also relates to processes for preparing the same; a pharmaceutical composition and formulation containing a derivative of piperlogumine; and use of the derivatives and analogs for treating cancer.

2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5] NONANE DERIVATIVES

The present invention provides a compound of Formula (I) or a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.

AMINOCYCLOHEXENE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY

Cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.

NITROGEN-CONTAINING BICYCLIC HETEROCYCLES FOR USE AS ANTIBACTERIALS

Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives hereof useful in methods of treatment of bacterial infections in mammals, particularly man.