The Mechanism of Catalysis of the Thio-Claisen Rearrangement
The cyclization-induced rearrangement mechanism proposed by Overman to account for nucleophilc catalysis of the thio-Claisen rearrangement has been tested by application of two criteria, viz., the secondary kinetic deuterium isotope effect at the β (side
Catalyst free annulative thioboration of unfunctionalized olefins
A direct and catalyst-free annulative thioboration of unfunctionalized olefins has been developed. In the presence of BCl3 as the sole boron source, the boryl group and thiol group are added to the C-C double bonds simultaneously. The boronic acids obtained can be protected to form synthetically ubiquitous pinacol boronate esters.