619335-63-6

Upstream product

• 31929-07-4 2-allyl-2-methyl-1,3-cyclohexanedione 
• 100-39-0 benzyl bromide 
• 619335-65-8 {[(2,6-dimethoxy-1-methylcyclohexa-2,5-dien-1-yl)methoxy]methyl}benzene 
• 619335-73-8 (2,6-dimethoxy-1-methylcyclohexa-2,5-dien-1-yl)methanol 
• 474956-28-0 6-allyl-6-methyl-1,4,8,11-tetraoxadispiro[4.1.4.3]tetradecane 
• 82478-17-9 methyl 2,6-dimethoxy-1-methylcyclohexa-2,5-diene-1-carboxylate 
• 856177-38-3 6-benzyloxymethyl-6-methyl-1,4,8,11-tetraoxadispiro[4.1.4.3]tetradecane 
• 856177-30-5 (E)-6-methyl-6-(1-propen-1-yl)-1,4,8,11-tetraoxadispiro[4.1.4.3]tetradecane 
• 856177-34-9 (6-methyl-1,4,8,11-tetraoxadispiro[4.1.4.3]tetradec-6-yl)methanol 
• 619335-62-5 (2R,3S)-2-Benzyloxymethyl-3-hydroxy-2-methyl-cyclohexanone 
• 619335-64-7 2-benzyloxymethyl-2-methylcyclohexane-1,3-dione 

Downstream Products

• 619335-74-9 (1S,3S)-2-hydroxymethyl-2-methylcyclohexane-1,3-diol 
• 856178-52-4 (2R,4aS,8aS)-hexahydro-4a-methyl-2-phenylbenzo[d][1,3]dioxin-5-one 
• 856178-55-7 (Z,2R,4aS,9aS)-4,4a,9,9a-tetrahydro-4a-methyl-2-phenylcyclohepta[d][1,3]dioxin-5(8H)-one 
• 619335-66-9 (2R,4aR,5S,8aS)-hexahydro-4a-methyl-2-phenyl-4H-benzo[d][1,3]dioxin-5-ol 
• 1365268-27-4 C₁₆H₂₄O₂ 
• 1365268-28-5 C₁₆H₂₂O₂ 
• 619335-62-5 (2R,3S)-2-Benzyloxymethyl-3-hydroxy-2-methyl-cyclohexanone 

Relevant academic research and scientific papers

Enantioselective total synthesis of (+)-bucidarasins A and C

In this paper, the first total synthesis of (+)-bucidarasins A and C is described. The chiral starting material was successfully obtained via reduction using a CBS catalyst and selective mono-TBS ether formation of trans -2-benzyloxymethyl-2-methylcyclohe

Preparation of new chiral building blocks: Highly enantioselective reduction of prochiral 1,3-cycloalkanediones possessing a methyl group and a protected hydroxymethyl group at their C2 position with Baker's yeast or CBS catalyst

Highly enantioselective reduction of five-, six-, seven-, and eight-membered prochiral 1,3-cycloalkanediones possessing a methyl group and a protected hydroxymethyl group at their C2 position with baker's yeast or CBS catalyst and a new efficient and general method for preparing the 1,3-cycloalkanediones have been developed. These baker's yeast mediated reductions were found to produce corresponding ketols with high optical purity (> 99% ee) and high yield. All of the prepared ketols and their derivatives, chiral building blocks, have been fully characterized, and their absolute configurations have been determined. These compounds would be useful for the convergent synthesis of complex natural products.

Preparation of new chiral building blocks via asymmetric catalysis

Highly enantio- and stereoselective preparation of some new chiral building blocks with baker's yeast or the CBS catalyst is described.