62127-42-8

Basic information

• Product Name: 1,1-difluorononane
• Synonyms: 1,1-DIFLUORONONANE
• CAS NO: 62127-42-8
• Molecular Formula: C₉H₁₈F₂
• Molecular Weight: 164.236
• Mol File: 62127-42-8.mol

Chemical Properties

• Boiling Point: 185.5°C at 760 mmHg
• Flash Point: 52.3°C
• Density: 0.871g/cm³
• Vapor Pressure: 0.953mmHg at 25°C
• Refractive Index: 1.383
• CAS DataBase Reference: 1,1-difluorononane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-difluorononane(62127-42-8)
• EPA Substance Registry System: 1,1-difluorononane(62127-42-8)

Safety Data

• Hazardous Substances Data: 62127-42-8(Hazardous Substances Data)

Upstream product

• 459-78-9 1,3-dibromo-1,1-difluorononane 
• 124-19-6 nonan-1-al 
• 1361128-81-5 nonane-1,1-diyl bis(trifluoromethanesulfonate) 
• 111-66-0 oct-1-ene 

Relevant articles and documents

Reactions of 1-fluoroalkyl triflates with nucleophiles and bases

A series of 1-fluoroalkyl triflates are prepared, isolated and characterized. Their reactions with a large variety of nucleophiles are described. From these reactions are obtained 1-fluoroalkyl nitriles, azides, formates, acetates, ethers, phenylthio ethers, triphenylphosphonium salts, benztriazoles, benzimidazoles, xanthates, iodides, bromides and chlorides, most in excellent yield.

Preparation of 1,1-difluoroalkanes from aldehydes via 1,1-bistriflates: Advantageous use of HF-Lewis base reagents

Alkane-1,1-bistriflates, prepared in excellent yields by reaction of aldehydes with triflic anhydride, are converted to their respective 1,1-difluoroalkanes in good to excellent yield through reaction with fluorinating agent, triethylaminetrishydrofluorid

Stereocontrolled generation of nucleophilic (Z)- or (E)-α- fluoroalkenylchromium reagents via carbon-fluorine bond activation: Highly stereoselective synthesis of (E)- or (Z)-β-fluoroallylic alcohols

Highly nucleophilic (Z)- or (E)-α-fluoroalkenylchromium species could be generated in a stereoselective manner via C-F bond activation of CBrF 2-containing molecules, and they reacted smoothly with various aldehydes to give (E)- or (Z)-β-fluoroallylic alcohol derivatives in high yields, respectively. The Royal Society of Chemistry.

Impact of fluorine substituents on the rates of nucleophilic aliphatic substitution and β-elimination

A measure of the quantitative effect of proximate fluorine substituents on the rates of SN2 and E2 reactions has been obtained through a study mainly of reactions of fluorinated n-alkyl bromides with weak base, strong nucleophile azide ion and strong base/nucleophile methoxide ion in the protic solvent methanol and the aprotic solvent, DMSO. The order of reactivity for SN2 reactions of azide in methanol at 50 °C was found to be: n-alkyl-Br > n-alkyl-CHFBr > n-perfluoroalkyl-CH2CH 2Br n-perfluoroalkyl-CH2Br > n-alkyl-CF2Br. Approximate relative rates of reaction were: 1, 0.20, 0.12, 1 × 10 -4, -5. The order of reactivity for E2 reactions was found to be: n-perfluoroalkyl-CH2CH2Br n-alkyl-CF2Br > n-alkyl-CHFBr > n-alkyl-Br. The approximate relative rates for reaction of methoxide in methanol at 50 °C were: 1100, 4.4, 1.9, 1.

Reductive defluorination of fluoroalkanes

The reaction of an excess of lithium powder and a catalytic amount of DTBB with primary, secondary and tertiary fluoroalkanes in the presence of a substoichiometric amount of 1,2-bis(trimethylsilyl)benzene 1 afforded the corresponding alkanes resulting from a fluorine-hydrogen exchange. The method could be extended to non-geminal difluorides. The effect of the disilylated compound in the naphthalene-catalysed lithiation of fluorobenzene and benzyl fluoride was also studied.